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[基于成像的免疫检查点抑制剂治疗实体瘤评估进展]

[Advances in Imaging-Based Evaluation of Solid Tumors Treated With Immune Checkpoint Inhibitors].

作者信息

Yang Shang-Ying, Liu Xin-Yu, Xue Hua-Dan, Jin Zheng-Yu, He Yong-Lan, Li Yuan

机构信息

Department of Radiology, National Clinical Research Center for Obstetric & Gynecologic Diseases,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Department of Obstetrics and Gynecology,National Clinical Research Center for Obstetric & Gynecologic Diseases,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024 Aug;46(4):610-618. doi: 10.3881/j.issn.1000-503X.15832.

DOI:10.3881/j.issn.1000-503X.15832
PMID:39223026
Abstract

Immune checkpoint inhibitors have shown remarkable benefits in the treatment of solid tumors,while the occurrence of atypical response patterns and immune-related adverse events during treatment challenges the accuracy of therapeutic evaluation.Medical imaging is crucial for the evaluation of immunotherapy.It enables the assessment of treatment efficacy via both morphological and functional ways and offers unique a predictive value when being combined with artificial intelligence.Here we review the recent research progress in imaging-based evaluation of solid tumors treated with immune checkpoint inhibitors.

摘要

免疫检查点抑制剂在实体瘤治疗中已显示出显著疗效,然而治疗期间非典型反应模式和免疫相关不良事件的出现对治疗评估的准确性提出了挑战。医学成像对于免疫治疗评估至关重要。它能够通过形态学和功能学方法评估治疗效果,并且与人工智能结合时具有独特的预测价值。在此,我们综述了基于成像的免疫检查点抑制剂治疗实体瘤评估的最新研究进展。

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