Al-Dossary Saif Khuzaim
Ophthalmology Consultant, King Faisal University, Al-Ahsa, Saudi Arabia.
Clin Ophthalmol. 2024 Aug 29;18:2427-2438. doi: 10.2147/OPTH.S474832. eCollection 2024.
This cross-sectional study aimed to investigate the associations between environmental and occupational factors and the prevalence of dry eye symptoms among participants from the Ahsa region of Saudi Arabia.
Participants from urban, rural, and suburban areas seeking medical care at primary health centers were recruited through systematic random sampling. Data on demographics, exposures, and ocular health were captured using a structured questionnaire. Dry eye symptoms were evaluated using the Ocular Surface Disease Index (OSDI), Impact of Dry Eye on Everyday Life (IDEEL), and Symptom Assessment in Dry Eye (SANDE) questionnaires. Logistic regression analysis examined the relationships between environmental/occupational factors and the prevalence of dry eye symptoms.
Key exposures included particulate matter (PM) (60%), low humidity (55%), wind/dust (50%), prolonged computer use (65%), and chemical irritants (45%). These factors were significantly associated with an increased prevalence of dry eye symptoms, with the following odds ratios (ORs): PM (1.85, 95% CI: 1.35-2.52), low humidity (1.45, 95% CI: 1.05-2.00), wind and dust (1.60, 95% CI: 1.20-2.14), prolonged computer use (2.10, 95% CI: 1.55-2.85), and chemical irritants (1.75, 95% CI: 1.30-2.35). All associations were statistically significant (p < 0.05). The use of protective equipment was associated with reduced odds of dry eye symptoms (OR 0.60, 95% CI: 0.42-0.85, p = 0.03).
This study identifies significant associations between specific environmental and occupational exposures and the prevalence of dry eye symptoms. Reducing modifiable exposures through policy, workplace enhancements, and clinical preventative strategies is essential to mitigate the burden of dry eye symptoms related to modern lifestyles and technology.
本横断面研究旨在调查沙特阿拉伯艾哈萨地区参与者的环境和职业因素与干眼症状患病率之间的关联。
通过系统随机抽样招募在初级卫生保健中心寻求医疗服务的城市、农村和郊区参与者。使用结构化问卷收集人口统计学、暴露情况和眼部健康数据。使用眼表疾病指数(OSDI)、干眼对日常生活的影响(IDEEL)和干眼症状评估(SANDE)问卷评估干眼症状。逻辑回归分析检验环境/职业因素与干眼症状患病率之间的关系。
主要暴露因素包括颗粒物(PM)(60%)、低湿度(55%)、风/灰尘(50%)、长时间使用电脑(65%)和化学刺激物(45%)。这些因素与干眼症状患病率增加显著相关,具体比值比(OR)如下:PM(1.85,95%置信区间:1.35 - 2.52)、低湿度(1.45,95%置信区间:1.05 - 2.00)、风/灰尘(1.60,95%置信区间:1.20 - 2.14)、长时间使用电脑(2.10,95%置信区间:1.55 - 2.85)和化学刺激物(1.75,95%置信区间:1.30 - 2.35)。所有关联均具有统计学意义(p < 0.05)。使用防护设备与干眼症状几率降低相关(OR 0.60,95%置信区间:0.42 - 0.85,p = 0.03)。
本研究确定了特定环境和职业暴露与干眼症状患病率之间的显著关联。通过政策、工作场所改进和临床预防策略减少可改变的暴露对于减轻与现代生活方式和技术相关的干眼症状负担至关重要。