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使用Novosorb可生物降解临时基质与Integra胶原蛋白-软骨素硅酮重建复杂上肢伤口的成本分析

Reconstruction of Complex Upper Extremity Wounds With Novosorb Biodegradable Temporizing Matrix Versus Integra Collagen-Chondroitin Silicone: A Cost Analysis.

作者信息

Jou Christopher, Chepla Kyle J

机构信息

Department of Plastic Surgery, Cleveland Clinic, Cleveland, Ohio.

Division of Plastic Surgery, MetroHealth Hospital, Cleveland, Ohio.

出版信息

Eplasty. 2024 Jun 18;24:e38. eCollection 2024.

Abstract

BACKGROUND

Reconstruction of upper extremity wounds with dermal matrices can reduce the length of hospitalization and surgical complexity without compromising functional outcomes. We aimed to compare costs between Novosorb biodegradable temporizing matrix (BTM) and Integra collagen-chondroitin silicone (CCS) bilayer.

METHODS

A chart review was performed for patients with isolated upper extremity traumatic wounds who underwent reconstruction with either BTM or CCS between January 2017 and May 2022. Demographic data, surgical procedures, outcomes, and costs were collected for analysis.

RESULTS

Twenty-seven patients were included: 18 BTM and 9 CCS. There were no differences in age, sex, wound size, or dermal template size. Skin grafting was required less frequently in BTM compared with CCS (44.4% vs 55.6%, = .013). Time to skin graft was longer in the BTM group (43.4 days vs 21.4 days, = .002). The BTM group experienced fewer complications (33.3% vs 55.6%, = .002). The mean number of secondary procedures required after template placement was 0.67 in BTM compared with 1.56 in CCS, = .049. When factoring in the cost of product, the cost of reconstruction with BTM was significantly lower than CCS ($1361.92 vs $3185.71, = .049).

CONCLUSIONS

Novosorb BTM is a more cost-effective option when compared with CCS for reconstruction of upper extremity soft tissue defects.

摘要

背景

使用真皮基质重建上肢伤口可缩短住院时间并降低手术复杂性,且不影响功能结局。我们旨在比较Novosorb可生物降解临时基质(BTM)和Integra胶原蛋白 - 软骨素硅酮(CCS)双层膜之间的成本。

方法

对2017年1月至2022年5月期间使用BTM或CCS进行重建的孤立上肢创伤性伤口患者进行病历回顾。收集人口统计学数据、手术程序、结局和成本进行分析。

结果

纳入27例患者:18例使用BTM,9例使用CCS。年龄、性别、伤口大小或真皮模板大小无差异。与CCS相比,BTM组皮肤移植的频率较低(44.4%对55.6%,P = 0.013)。BTM组进行皮肤移植的时间更长(43.4天对21.4天,P = 0.002)。BTM组的并发症较少(33.3%对55.6%,P = 0.002)。放置模板后所需的二次手术平均次数,BTM组为0.67次,而CCS组为1.56次,P = 0.049。考虑产品成本后,使用BTM进行重建的成本显著低于CCS(1361.92美元对3185.71美元,P = 0.049)。

结论

与CCS相比,Novosorb BTM是重建上肢软组织缺损更具成本效益的选择。

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