Abaydi Mohamed Hamza, Dhimene Safae, Ech-Chenbouli Amine, El Boussaadani Badre, Raissuni Zainab
Cardiology Department, Mohamed VI University Hospital of Tangier; Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Street of Rabat, Km 17, BP 398, 90100 Tangier, Morocco.
Eur Heart J Case Rep. 2024 Sep 1;8(9):ytae437. doi: 10.1093/ehjcr/ytae437. eCollection 2024 Sep.
Aortobronchial fistulas (ABFs) are rare but potentially life-threatening conditions, often presenting with haemoptysis. They can develop following various thoracic aortic conditions or procedures.
A 70-year-old patient with a history of descending aorta replacement and ischaemic stroke presented with chest pain and upper gastrointestinal bleeding. Imaging revealed a fistula between the aortic prosthesis and the lung, along with other cardiovascular abnormalities. Despite the indication for anticoagulant therapy, tranexamic acid was initiated due to bleeding risk. The patient showed clinical improvement with tranexamic acid treatment but experienced recurrence of bleeding after discontinuation. Endovascular treatment for the contained rupture at the proximal stent anastomosis was indicated.
Haemoptysis is the primary symptom of ABFs, often recurring until the fistula enlarges. Postoperative aortic fistulas into the airways are uncommon and can occur years after surgery. Thoracic endovascular aortic repair has become the primary treatment for high-risk patients with thoracic aortic disease. Various diagnostic modalities can visualize a fistula tract, but practical visualization is rare. Untreated ABFs invariably lead to death.
This case highlights the challenges in diagnosing and managing ABFs, emphasizing the need for a multidisciplinary approach and regular follow-up. Patient education and prompt reporting of symptoms are essential. Early intervention upon suspicion of recurrence is crucial for optimizing patient outcomes.
主动脉支气管瘘(ABF)较为罕见,但可能危及生命,常表现为咯血。它可在各种胸主动脉疾病或手术后发生。
一名70岁患者,有降主动脉置换术和缺血性中风病史,出现胸痛和上消化道出血。影像学检查显示主动脉假体与肺部之间存在瘘管,同时伴有其他心血管异常。尽管有抗凝治疗指征,但由于出血风险,开始使用氨甲环酸。患者经氨甲环酸治疗后临床症状改善,但停药后出血复发。因此,对近端支架吻合处的局限性破裂进行血管内治疗。
咯血是ABF的主要症状,通常会反复出现,直至瘘管扩大。术后主动脉气道瘘并不常见,可在手术后数年发生。胸主动脉腔内修复术已成为高危胸主动脉疾病患者的主要治疗方法。各种诊断方法可显示瘘管,但实际可视化很少见。未经治疗的ABF必然导致死亡。
本病例突出了ABF诊断和管理中的挑战,强调了多学科方法和定期随访的必要性。患者教育和症状的及时报告至关重要。怀疑复发时早期干预对于优化患者预后至关重要。