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用于研究单分子化学反应的技术。

Technologies for investigating single-molecule chemical reactions.

作者信息

Gao Chunyan, Gao Qinghua, Zhao Cong, Huo Yani, Zhang Zhizhuo, Yang Jinlong, Jia Chuancheng, Guo Xuefeng

机构信息

Center of Single-Molecule Sciences, Institute of Modern Optics, Frontiers Science Center for New Organic Matter, Tianjin Key Laboratory of Micro-Scale Optical Information Science and Technology, College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300350, China.

Hefei National Research Center for Physical Sciences at Microscale, University of Science and Technology of China, Hefei 230026, China.

出版信息

Natl Sci Rev. 2024 Jul 9;11(8):nwae236. doi: 10.1093/nsr/nwae236. eCollection 2024 Aug.

DOI:10.1093/nsr/nwae236
PMID:39224448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11367963/
Abstract

Single molecules, the smallest independently stable units in the material world, serve as the fundamental building blocks of matter. Among different branches of single-molecule sciences, single-molecule chemical reactions, by revealing the behavior and properties of individual molecules at the molecular scale, are particularly attractive because they can advance the understanding of chemical reaction mechanisms and help to address key scientific problems in broad fields such as physics, chemistry, biology and materials science. This review provides a timely, comprehensive overview of single-molecule chemical reactions based on various technical platforms such as scanning probe microscopy, single-molecule junction, single-molecule nanostructure, single-molecule fluorescence detection and crossed molecular beam. We present multidimensional analyses of single-molecule chemical reactions, offering new perspectives for research in different areas, such as photocatalysis/electrocatalysis, organic reactions, surface reactions and biological reactions. Finally, we discuss the opportunities and challenges in this thriving field of single-molecule chemical reactions.

摘要

单分子是物质世界中最小的独立稳定单元，是构成物质的基本基石。在单分子科学的不同分支中，单分子化学反应通过在分子尺度上揭示单个分子的行为和性质，显得尤为引人关注，因为它们能够推动对化学反应机理的理解，并有助于解决物理、化学、生物学和材料科学等广泛领域的关键科学问题。本综述基于扫描探针显微镜、单分子结、单分子纳米结构、单分子荧光检测和交叉分子束等各种技术平台，及时、全面地概述了单分子化学反应。我们展示了单分子化学反应的多维分析，为光催化/电催化、有机反应、表面反应和生物反应等不同领域的研究提供了新的视角。最后，我们讨论了这个蓬勃发展的单分子化学反应领域的机遇与挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/f80adc259e18/nwae236fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/9770bf85a163/nwae236fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/9ff1fec34f82/nwae236fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/b8bed67d6bf0/nwae236fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/46b9e367d520/nwae236fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/7c7915438e34/nwae236fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/5f493fb4a192/nwae236fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/4f334c9bf9f9/nwae236fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/c5d36719a3d8/nwae236fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/e2f4175ebe59/nwae236fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/f80adc259e18/nwae236fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/9770bf85a163/nwae236fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/9ff1fec34f82/nwae236fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/b8bed67d6bf0/nwae236fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/46b9e367d520/nwae236fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/7c7915438e34/nwae236fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/5f493fb4a192/nwae236fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/4f334c9bf9f9/nwae236fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/c5d36719a3d8/nwae236fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/e2f4175ebe59/nwae236fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/882e/11367963/f80adc259e18/nwae236fig10.jpg

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