Csaba G, Németh G, Kovács P, Vargha P, Vas A
Biosystems. 1985;17(3):227-31. doi: 10.1016/0303-2647(85)90076-0.
The polypeptide hormones insulin, glucagon, thyrotropin (TSH), pregnant mare serum gonadotropin (PMSG) and adrenocorticotropin (ACTH) stimulated the growth of the Tetrahymena, and the non-hormone polypeptides (bovine serum albumin (BSA), protamine) had a similar effect. Re-exposure after 24 h accounted for a greater growth stimulation than pre-exposure alone in cultures treated with TSH and PMSG, and re-exposure after 7 days had such effect in all polypeptide-treated cultures. It follows that the non-hormone polypeptides had a similar imprinting potential to the polypeptide hormone. The non-hormone polypeptides were also able to cross-imprint for one another, i.e. pre-exposure to one enhanced the binding capacity of the cells for the other on re-exposure, and vice versa. A single treatment with a polypeptide hormone or a non-hormone polypeptide did in itself stimulate the growth of the Tetrahymena for as long as 1 week.
胰岛素、胰高血糖素、促甲状腺激素（TSH）、孕马血清促性腺激素（PMSG）和促肾上腺皮质激素（ACTH）等多肽激素刺激了四膜虫的生长，非激素多肽（牛血清白蛋白（BSA）、鱼精蛋白）也有类似作用。在TSH和PMSG处理的培养物中，24小时后再次暴露比单独预暴露能产生更大的生长刺激，而7天后再次暴露在所有多肽处理的培养物中都有这种效果。由此可见，非激素多肽与多肽激素具有相似的印记潜力。非激素多肽之间也能够相互交叉印记，即预暴露于一种多肽会增强细胞在再次暴露时对另一种多肽的结合能力，反之亦然。用多肽激素或非激素多肽进行单次处理本身就能刺激四膜虫生长长达1周。
