一例以不明原因发热复发伴肺栓塞起病的白塞病疑难诊断：病例报告
A Challenging Diagnosis of Behçet's Disease Starting from Unexplained Fever Recurrence with Pulmonary Embolism: A Case Report.
作者信息
Liu Rong, Ji Tingfen, Jiang Yixia, Li Hequan
机构信息
Department of Respiratory Medicine, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China.
Department of Respiratory and Critical Care Medicine, Lishui People's Hospital, Lishui, Zhejiang, People's Republic of China.
出版信息
J Inflamm Res. 2024 Aug 29;17:5801-5805. doi: 10.2147/JIR.S466840. eCollection 2024.
PURPOSE
Recurrent inflammatory fevers with multisystem involvement occur clinically and may indicate an autoimmune disease.
CASE
We present a young male diagnosed with pulmonary embolism who experienced recurrent fever during hospitalization and was unresponsive to antibiotics and antipyretics. A follow-up history revealed chronic oral and genital ulcers, leading to a final diagnosis of Behçet's disease.
CONCLUSION
The patient's temperature normalized rapidly after corticosteroid therapy, and infection markers returned to normal. Complete remission was achieved with immunosuppression and glucocorticoid therapy. Reporting characteristics, treatment experience, and outcomes of such cases are essential to inform future diagnosis and management strategies.
目的
临床上会出现伴有多系统受累的复发性炎症性发热，这可能提示自身免疫性疾病。
病例
我们报告一名年轻男性，诊断为肺栓塞，住院期间反复发热，对抗生素和退烧药无反应。进一步询问病史发现有慢性口腔和生殖器溃疡，最终诊断为白塞病。
结论
患者在接受糖皮质激素治疗后体温迅速恢复正常，感染指标也恢复正常。通过免疫抑制和糖皮质激素治疗实现了完全缓解。报告此类病例的特征、治疗经验和结果对于指导未来的诊断和管理策略至关重要。
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