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中国产后抑郁症的患病率及相关因素:一项基于医院的横断面研究。

Prevalence and risk factors of postpartum depression in China: A hospital-based cross-sectional study.

机构信息

Department of Maternal and Child Health, Xiangya School of Public Health, Central South University, Changsha 410078, China.

Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

J Affect Disord. 2021 Mar 1;282:1096-1100. doi: 10.1016/j.jad.2021.01.012. Epub 2021 Jan 10.

Abstract

BACKGROUND

Postpartum depression (PPD) is a major public health problem worldwide, which adversely affects maternal and infant health. The purpose of this study was to determine the prevalence and related factors of postpartum depression in Chinese puerperium women.

METHODS

A cross-sectional study was conducted in Baoan Maternal and Child Health Hospital located in the west of Shenzhen, China. The Chinese version of the Edinburgh Postpartum Depression Scale (EPDS) was used to screen PPD. A score of ≥10 was used as the threshold of postpartum depression.

RESULTS

A total of 4813 puerperal women were included in this study, 11.5% of whom were considered to have PPD. Multivariate logistic regression analysis found that family history of mental illness (OR = 1.94; 95% CI, 1.05-3.57; P = 0.033), living with parents-in-law (OR = 1.41; 95% CI, 1.16-1.72; P < 0.001), anxiety during pregnancy (OR = 3.66; 95% CI, 2.97-4. 52; P < 0.001), depression during pregnancy (OR = 4.25; 95% CI, 3.28-5.50; P < 0.001), and stressful life events (OR = 1.50; 95% CI, 1.03-2.20; P = 0.036) were associated with the high prevalence of PPD.

LIMITATIONS

The cross-sectional survey cannot assess direct causality. EPDS is just a screening tool and not a diagnostic one.

CONCLUSION

Postpartum depression is a common disease in Chinese puerperal population. High-risk pregnant women with postpartum depression need routine screening and targeted intervention for PPD.

摘要

背景

产后抑郁症(PPD)是全球一个主要的公共卫生问题,对母婴健康均有不利影响。本研究旨在确定中国产褥期妇女产后抑郁症的患病率及其相关因素。

方法

采用横断面研究方法,在中国深圳市西部的宝安区妇幼保健院进行。使用中文版爱丁堡产后抑郁量表(EPDS)筛查产后抑郁症。以≥10 分为产后抑郁症的阈值。

结果

本研究共纳入 4813 名产褥期妇女,其中 11.5%被认为患有产后抑郁症。多因素 logistic 回归分析发现,精神疾病家族史(OR=1.94;95%CI,1.05-3.57;P=0.033)、与公婆同住(OR=1.41;95%CI,1.16-1.72;P<0.001)、妊娠焦虑(OR=3.66;95%CI,2.97-4.52;P<0.001)、妊娠抑郁(OR=4.25;95%CI,3.28-5.50;P<0.001)和生活压力事件(OR=1.50;95%CI,1.03-2.20;P=0.036)与 PPD 高患病率相关。

局限性

横断面调查不能评估直接因果关系。EPDS 只是一种筛查工具,而不是诊断工具。

结论

产后抑郁症是中国产褥期妇女的一种常见疾病。患有产后抑郁症的高危孕妇需要常规筛查,并针对 PPD 进行有针对性的干预。

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