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预防毒葛接触性皮炎的创新。

Innovation in prevention of poison oak contact dermatitis.

机构信息

University of California, Berkeley, CA, 94720, USA.

University of California, San Francisco, CA, 94143, USA.

出版信息

Arch Dermatol Res. 2024 Sep 3;316(8):596. doi: 10.1007/s00403-024-03347-9.

DOI:10.1007/s00403-024-03347-9
PMID:39225822
Abstract

Poison oak-induced contact dermatitis poses a significant challenge due to its urushiol oil-induced allergic reactions. Conventional preventive measures like avoidance and post-exposure cleansing are often impractical, necessitating innovative strategies. This comprehensive review explores emerging technologies and formulations for preventing poison oak dermatitis. Literature search via PubMed and Covidence identified 13 relevant studies, with six discussing preventive measures. Barrier methods, including occlusive creams and protective clothing, showed promise in reducing dermatitis risk. Immunotherapy, although investigated, requires further development. Complete avoidance, while effective, is often impractical. The complexity of poison oak management underscores the need for ongoing research to develop more effective preventive measures. This review highlights the current landscape, identifies gaps in knowledge, and emphasizes the importance of continued research for improved prevention and management of poison oak-induced dermatitis.

摘要

毒葛引起的接触性皮炎是一个重大的挑战,因为它的漆酚油引起的过敏反应。传统的预防措施,如避免接触和暴露后清洗,往往不切实际,需要创新的策略。本综述探讨了预防毒葛性皮炎的新兴技术和制剂。通过 PubMed 和 Covidence 进行文献检索,确定了 13 项相关研究,其中 6 项讨论了预防措施。屏障方法,包括闭塞乳膏和防护服,显示出降低皮炎风险的潜力。免疫疗法虽然有研究,但需要进一步发展。完全避免虽然有效,但往往不切实际。毒葛管理的复杂性突出表明需要进行持续的研究,以开发更有效的预防措施。本综述强调了当前的研究现状,指出了知识空白,并强调了继续研究的重要性,以改善毒葛引起的皮炎的预防和管理。

相似文献

1
Innovation in prevention of poison oak contact dermatitis.预防毒葛接触性皮炎的创新。
Arch Dermatol Res. 2024 Sep 3;316(8):596. doi: 10.1007/s00403-024-03347-9.
2
Poison Ivy, Oak, and Sumac Dermatitis: What Is Known and What Is New?毒葛、毒栎和毒漆树皮炎:已知和新知?
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Am J Contact Dermat. 1997 Sep;8(3):144-9.
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Toxicodendron dermatitis: poison ivy, oak, and sumac.漆树皮炎:毒葛、毒橡树和毒漆树。
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A study of cross-reactions between mango contact allergens and urushiol.芒果接触性变应原与漆酚之间交叉反应的研究。
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Exploring the mango-poison ivy connection: the riddle of discriminative plant dermatitis.探索芒果与毒葛的关联:鉴别性植物性皮炎之谜。
Contact Dermatitis. 2005 Jan;52(1):3-5. doi: 10.1111/j.0105-1873.2005.00454.x.
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Preservation of allergic contact dermatitis to poison ivy (urushiol) in late HIV disease. The implications and relevance to immunotherapy with contact allergens.晚期HIV疾病中对毒藤(漆酚)过敏性接触性皮炎的维持。其对接触性变应原免疫治疗的影响及相关性。
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本文引用的文献

1
Poison Ivy, Oak, and Sumac Dermatitis: What Is Known and What Is New?毒葛、毒栎和毒漆树皮炎:已知和新知?
Dermatitis. 2019 May/Jun;30(3):183-190. doi: 10.1097/DER.0000000000000472.
2
Toxicodendron dermatitis: poison ivy, oak, and sumac.漆树皮炎:毒葛、毒橡树和毒漆树。
Wilderness Environ Med. 2006 Summer;17(2):120-8. doi: 10.1580/pr31-05.1.
3
Regulation of the contact sensitivity response to urushiol with anti-urushiol monoclonal antibody ALG 991.用抗漆酚单克隆抗体ALG 991调节对漆酚的接触敏感性反应。
Arch Dermatol Res. 1999 Dec;291(12):652-8. doi: 10.1007/s004030050470.
4
Prevention of poison ivy and poison oak allergic contact dermatitis by quaternium-18 bentonite.季铵盐-18膨润土预防毒葛和毒栎过敏性接触性皮炎。
J Am Acad Dermatol. 1995 Aug;33(2 Pt 1):212-6. doi: 10.1016/0190-9622(95)90237-6.