Suppr超能文献

头颈部淋巴水肿——我们处于何处,以及我们的前进方向。

Lymphedema of the Head and Neck-Where Do We Stand and Where We Are Headed.

机构信息

School of Medicine, University of Miami Miller, Miami, FL.

Department of Plastic Surgery, Center for Lymphedema Research and Reconstruction, Cleveland Clinic Foundation, Cleveland, OH.

出版信息

J Craniofac Surg. 2024 Oct 1;35(7):2045-2048. doi: 10.1097/SCS.0000000000010505. Epub 2024 Sep 3.

Abstract

Great advancements have been made in the management of lymphedema of the extremities with lymphatic surgery. However, lymphedema of other regions, including head and neck, has remained neglected. Recent discovery of lymphatic system in the brain and the communication between intracranial and paracranial lymphatic systems has drawn attention to the head and neck lymphatics. Lymphedema of the head and neck region can result from inherent abnormality of the lymphatic system (primary) or be caused by accidental or iatrogenic injury to lymphatics (secondary). The head and neck contain a large network of lymphatic tissue. They may be affected by direct tumor infiltration, surgical resection of tumors and surrounding cancer tissue, and/or radiotherapy. Proper screening and counseling of patients before facial aesthetic procedures may avoid managing the distress of lymphedema postprocedure. Progression of head and neck lymphedema (HNL) can lead to chronic inflammatory, fibrosclerotic, and fibrofatty deposition, resulting in permanent deformity and disability. Patients may experience functional impairment, including skin changes, pain, range of motion limitations, contracture, dysphagia, dysarthria, dyspnea, and trismus, all leading to reduced quality of life. Despite these known disabilities, HNL is underdiagnosed due to a lack of awareness about this entity and of tools available for measuring internal or external swelling. The authors' article comprehensively reviews the current diagnostic methods and management strategies and what lies ahead.

摘要

在淋巴外科学的管理下,四肢的淋巴水肿已经取得了很大的进展。然而,其他区域的淋巴水肿,包括头颈部,仍然被忽视。最近在大脑中发现了淋巴管以及颅内和颅外淋巴管之间的交流,这引起了对头颈部淋巴管的关注。头颈部的淋巴水肿可能是由于淋巴管的固有异常(原发性)引起的,也可能是由于淋巴管的意外或医源性损伤(继发性)引起的。头颈部包含一个大型的淋巴组织网络。它们可能受到直接肿瘤浸润、肿瘤和周围癌组织的手术切除以及/或放疗的影响。在进行面部美容手术之前,对患者进行适当的筛查和咨询,可能可以避免术后处理淋巴水肿带来的困扰。头颈部淋巴水肿(HNL)的进展可导致慢性炎症、纤维化和纤维脂肪沉积,导致永久性畸形和残疾。患者可能会出现功能障碍,包括皮肤变化、疼痛、运动范围受限、挛缩、吞咽困难、构音障碍、呼吸困难和牙关紧闭,所有这些都会导致生活质量下降。尽管存在这些已知的残疾,但由于对该实体缺乏认识以及缺乏测量内部或外部肿胀的工具,HNL 的诊断仍然不足。作者的文章全面回顾了当前的诊断方法和管理策略,以及未来的发展方向。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验