Key Laboratory of Pollution Control Chemistry and Environmental Functional Materials for Qinghai-Tibet Plateau of the National Ethnic Affairs Commission, School of Chemistry and Environment, Southwest Minzu University, Chengdu 610041, China; Institute of Nanochemistry and Nanobiology, Shanghai University, Shanghai 200444, China.
Key Laboratory of Pollution Control Chemistry and Environmental Functional Materials for Qinghai-Tibet Plateau of the National Ethnic Affairs Commission, School of Chemistry and Environment, Southwest Minzu University, Chengdu 610041, China.
NanoImpact. 2024 Oct;36:100528. doi: 10.1016/j.impact.2024.100528. Epub 2024 Sep 1.
Vanadium dioxide (VO) is an excellent phase transition material widely used in various applications, and thus inevitably enters the environment via different routes and encounters various organisms. Nonetheless, limited information is available on the environmental hazards of VO. In this study, we investigated the impact of two commercial VO particles, nanosized S-VO and micro-sized M-VO on the white rot fungus Phanerochaete chrysosporium. The growth of P. chrysosporium is significantly affected by VO particles, with S-VO displaying a higher inhibitory effect on weight gain. In addition, VO at high concentrations inhibits the formation of fungal fibrous hyphae and disrupts the integrity of fungus cells as evidenced by the cell membrane damage and the loss of cytoplasm. Notably, at 200 μg/mL, S-VO completely alters the morphology of P. chrysosporium, while the M-VO treatment does not affect the mycelium formation of P. chrysosporium. Additionally, VO particles inhibit the laccase activity secreted by P. chrysosporium, and thus prevent the dye decoloration and sawdust decomposition by P. chrysosporium. The mechanism underlying this toxicity is related to the dissolution of VO and the oxidative stress induced by VO. Overall, our findings suggest that VO nanoparticles pose significant environmental hazards and risks to white rot fungi.
二氧化钒（VO）是一种广泛应用于各种应用的优异相变材料，因此不可避免地通过不同途径进入环境并遇到各种生物体。然而，关于 VO 的环境危害的信息有限。在这项研究中，我们研究了两种商业 VO 颗粒，纳米 S-VO 和微米 M-VO 对白腐真菌糙皮侧耳（Phanerochaete chrysosporium）的影响。VO 颗粒对 P. chrysosporium 的生长有显著影响，S-VO 对增重的抑制作用更高。此外，高浓度的 VO 抑制真菌纤维状菌丝的形成，并破坏真菌细胞的完整性，这表现为细胞膜损伤和细胞质流失。值得注意的是，在 200μg/mL 时，S-VO 完全改变了 P. chrysosporium 的形态，而 M-VO 处理不影响 P. chrysosporium 的菌丝体形成。此外，VO 颗粒抑制 P. chrysosporium 分泌的漆酶活性，从而阻止 P. chrysosporium 对染料脱色和木屑分解。这种毒性的机制与 VO 的溶解和 VO 诱导的氧化应激有关。总的来说，我们的研究结果表明，VO 纳米颗粒对白色腐真菌具有重大的环境危害和风险。
