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在结核接触者外周血单核细胞中检测DNA与早期结核病的血液RNA特征无关。

Detection of DNA in peripheral blood mononuclear cells of tuberculosis contacts does not associate with blood RNA signatures for incipient tuberculosis.

作者信息

Rosenheim Joshua, Abebe Markos, Belay Mulugeta, Tulu Begna, Tayachew Dawit, Tegegn Metasebia, Younis Sidra, Jolliffe David A, Aseffa Abraham, Ameni Gobena, Reece Stephen T, Noursadeghi Mahdad, Martineau Adrian R

机构信息

Division of Infection and Immunity, University College London, London, UK.

Armauer Hansen Research Institute, Addis Ababa, Ethiopia.

出版信息

Eur Respir J. 2024 Dec 12;64(6). doi: 10.1183/13993003.00479-2024. Print 2024 Dec.

DOI:10.1183/13993003.00479-2024
PMID:39227070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11635380/
Abstract

https://bit.ly/4dliODg

摘要

这看起来是一个链接，无法直接翻译为中文，其对应的中文表述为：https://bit.ly/4dliODg （可直接保留该链接形式） 。若你想表达的不是这个意思，请提供正确的文本内容。

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Detection of DNA in peripheral blood mononuclear cells of tuberculosis contacts does not associate with blood RNA signatures for incipient tuberculosis.在结核接触者外周血单核细胞中检测DNA与早期结核病的血液RNA特征无关。
Eur Respir J. 2024 Dec 12;64(6). doi: 10.1183/13993003.00479-2024. Print 2024 Dec.
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PET-CT-guided characterisation of progressive, preclinical tuberculosis infection and its association with low-level circulating Mycobacterium tuberculosis DNA in household contacts in Leicester, UK: a prospective cohort study.英国莱斯特家庭接触者中PET-CT引导下对进展性临床前结核感染的特征分析及其与低水平循环结核分枝杆菌DNA的关联：一项前瞻性队列研究
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本文引用的文献

1
Resolution of tuberculosis blood RNA signatures fails to discriminate persistent sputum culture positivity after 8 weeks of anti-tuberculous treatment.抗结核治疗 8 周后，结核血液 RNA 特征的消退未能区分持续的痰培养阳性。
Eur Respir J. 2024 Nov 21;64(5). doi: 10.1183/13993003.00457-2024. Print 2024 Nov.
2
Detection of Mycobacterium tuberculosis DNA in CD34 peripheral blood mononuclear cells of adults with tuberculosis infection and disease.检测成人结核感染和疾病患者外周血单个核细胞中的结核分枝杆菌 DNA。
Int J Infect Dis. 2024 Apr;141S:106999. doi: 10.1016/j.ijid.2024.106999. Epub 2024 Mar 7.
3
Toward a molecular microbial blood test for tuberculosis infection.
Int J Infect Dis. 2024 Apr;141S:106988. doi: 10.1016/j.ijid.2024.106988. Epub 2024 Feb 28.
4
Detection of complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study.无症状结核接触者外周血单个核细胞中复杂 DNA 的检测：一项观察性研究。
Lancet Microbe. 2021 Jun;2(6):e267-e275. doi: 10.1016/S2666-5247(21)00043-4.
5
Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.结核疾病宿主转录组特征降低的鉴定及基于数字 PCR 的验证和定量。
Front Immunol. 2021 Mar 2;12:637164. doi: 10.3389/fimmu.2021.637164. eCollection 2021.
6
Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis.简明全血转录特征用于早期结核病：系统评价和患者水平合并荟萃分析。
Lancet Respir Med. 2020 Apr;8(4):395-406. doi: 10.1016/S2213-2600(19)30282-6. Epub 2020 Jan 17.
7
Blood Transcriptomic Stratification of Short-term Risk in Contacts of Tuberculosis.结核接触者短期风险的血液转录组分层。
Clin Infect Dis. 2020 Feb 14;70(5):731-737. doi: 10.1093/cid/ciz252.
8
Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.潜伏性和亚临床性结核病：感染早期阶段和进展的临床评估。
Clin Microbiol Rev. 2018 Jul 18;31(4). doi: 10.1128/CMR.00021-18. Print 2018 Oct.
9
Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.四基因泛非血液特征预测结核病进展
Am J Respir Crit Care Med. 2018 May 1;197(9):1198-1208. doi: 10.1164/rccm.201711-2340OC.
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PLoS One. 2017 Jan 3;12(1):e0169119. doi: 10.1371/journal.pone.0169119. eCollection 2017.