Associate Staff, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, Cleveland, OH
Adult Endocrinologist, Department of Endocrinology, Diabetes, and Metabolism, Maine Medical Center, Maine Health, Sarborough, ME.
Cleve Clin J Med. 2024 Sep 3;91(9):553-562. doi: 10.3949/ccjm.91a.23072.
Primary adrenal insufficiency is rare but serious; it puts patients at risk of acute decompensation and adrenal crisis due to insufficient cortisol and aldosterone production. Further, its diagnosis is often delayed, or it is mistaken for secondary adrenal insufficiency, which can have life-threatening consequences. Early recognition and appropriate treatment can greatly improve patient outcomes and quality of life.
原发性肾上腺功能不全罕见但严重；由于皮质醇和醛固酮生成不足，患者有发生急性失代偿和肾上腺危象的风险。此外，其诊断往往被延迟，或被误诊为继发性肾上腺功能不全，这可能会有生命危险。早期识别和适当的治疗可以大大改善患者的预后和生活质量。
