Dalery J, Claustrat B, Brun J, Terra J L, Chazot G, de Villard R
Encephale. 1985 Jan-Feb;11(1):25-8.
From a biological study of 8 patients with anorexia nervosa and an analysis of the daily profiles of gonadotropins, cortisol and melatonin, the authors discuss the possible relationship between anorexia nervosa and affective disorders. At the initial phase of the illness, plasmatic levels of FSH, LH and oestradiol were very low. 24-hour plasma cortisol values were comparable with those of a depressive population; when weight loss was equal to or higher than 25% of the initial weight, there was no suppression by dexamethasone. The daily profile of melatonin was maintained, with melatonin plasma levels significatively higher than in a control group of depressed patients.
通过对8例神经性厌食症患者的生物学研究以及对促性腺激素、皮质醇和褪黑素的每日变化情况分析，作者探讨了神经性厌食症与情感障碍之间的可能关系。在疾病初期，促卵泡生成素（FSH）、促黄体生成素（LH）和雌二醇的血浆水平非常低。24小时血浆皮质醇值与抑郁症患者群体相当；当体重减轻等于或高于初始体重的25%时，地塞米松无法抑制其水平。褪黑素的每日变化情况保持不变，其血浆水平显著高于抑郁症患者对照组。
