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居住型养老机构中预防跌倒的运动干预的定性比较分析。

Qualitative Comparative Analysis of exercise interventions for fall prevention in residential aged care facilities.

机构信息

Rehabilitation, Aged and Extended Care, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University of South Australia, Bedford Park, Australia.

Rehabilitation, Aged and Extended Care Flinders Medical Centre, GPO Box 2100, Adelaide, SA, 5001, Australia.

出版信息

BMC Geriatr. 2024 Sep 3;24(1):728. doi: 10.1186/s12877-024-05246-0.

Abstract

BACKGROUND

Exercise interventions are highly effective at preventing falls in older people living in the community. In residential aged care facilities (RACFs), however, the evidence for effectiveness is highly variable, warranting exploration of drivers of successful trials. This study aims to identify the conditions of randomised controlled trials (RCTs) that are associated with reducing falls in RACFs and test whether it can explain the variability.

METHODS

RCTs testing exercise interventions in RACFs compared to usual care, reporting rate or risk of falls from the 2018 Cochrane Collaboration review and a search update to December 2022 were included. Two authors independently extracted and coded trial conditions and outcomes according to a theory developed from prior Intervention Component Analysis. Trial outcomes were coded as successful or unsuccessful based on point estimates for the rate or risk ratio for falls, or p value. Qualitative Comparative Analysis (QCA), utilising Boolean minimisation theory, was conducted to determine the key conditions driving trial success. A subgroup meta-analysis and the GRADE approach was applied to the final theory.

RESULTS

Eighteen trials undertaken in 11 countries with 2,287 residents were included. Participants were predominately ambulant females aged 70 to 80 with cognitive impairment. Most interventions were fully supervised or supervised at the start of the intervention. QCA identified two configurations as drivers of successful exercise falls prevention programs: (i) group exercise that is moderate or low intensity, or (ii) for independent ambulatory residents, exercise for more than 1 h per week. The combination of configuration (i) and (ii) had consistency and total coverage scores of 1, indicating all trials were explained. This combination was associated with a reduction in falls (rate ratio 0.45, 95%CI 0.34 to 0.59; risk ratio 0.66, 95%CI 0.53 to 0.82; low certainty evidence).

CONCLUSION

To successfully reduce falls in RACFs, exercise programs should provide continuous supervised moderate-intensity group exercise. For programs that mostly include independent ambulatory residents, exercise for at least 80 min per week should be provided. As many current residents are frail, tailored exercise is likely necessary and an individualised dose may be required. Future trials should test exercise interventions for less mobile residents.

摘要

背景

运动干预措施在预防社区中老年人跌倒方面非常有效。然而,在养老院中,其有效性的证据差异很大,有必要探索成功试验的驱动因素。本研究旨在确定与减少养老院跌倒相关的随机对照试验(RCT)的条件,并测试其是否可以解释这种变异性。

方法

纳入了 2018 年 Cochrane 协作组综述和 2022 年 12 月更新搜索中测试养老院中运动干预措施与常规护理的 RCT,报告跌倒发生率或风险。两位作者根据先前的干预成分分析理论独立提取和编码试验条件和结局。根据跌倒发生率或风险比的点估计值或 p 值,将试验结局编码为成功或失败。利用布尔最小化理论进行定性比较分析(QCA),以确定驱动试验成功的关键条件。对最终理论进行亚组荟萃分析和 GRADE 方法。

结果

纳入了来自 11 个国家的 18 项试验,共 2287 名居民。参与者主要为 70 至 80 岁有认知障碍的可活动女性。大多数干预措施都是完全监督或在干预开始时进行监督。QCA 确定了两个配置作为成功的运动跌倒预防计划的驱动因素:(i)中等或低强度的小组运动,或(ii)对于独立活动的居民,每周运动超过 1 小时。配置(i)和(ii)的组合具有一致性和总覆盖率得分为 1,表明所有试验都得到了解释。这种组合与跌倒减少相关(发生率比 0.45,95%CI 0.34 至 0.59;风险比 0.66,95%CI 0.53 至 0.82;低确定性证据)。

结论

为了成功降低养老院的跌倒率,运动计划应提供持续监督的中等强度小组运动。对于主要包括独立活动居民的计划,每周应进行至少 80 分钟的运动。由于许多现有居民身体虚弱,可能需要量身定制的运动,并且可能需要个体化剂量。未来的试验应测试针对行动不便居民的运动干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b6b/11370059/ac97fcf340c6/12877_2024_5246_Fig1_HTML.jpg

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