慢性阻塞性肺疾病患者报告结局测量的计算机化自适应测试的心理测量学特性。

Psychometric properties of computerized adaptive testing for chronic obstructive pulmonary disease patient-reported outcome measurement.

机构信息

Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Henan Province & Education Ministry of P.R. China, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, 450046, China.

Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, 450046, China.

出版信息

Health Qual Life Outcomes. 2024 Sep 4;22(1):73. doi: 10.1186/s12955-024-02291-6.

DOI:10.1186/s12955-024-02291-6

PMID:39227972

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11373186/

Abstract

BACKGROUND

Computerized adaptive testing (CAT) is an effective way to reduce time, repetitious redundancy, and respond burden, and has been used to measure outcomes in many diseases. This study aimed to develop and validate a comprehensive disease-specific CAT for chronic obstructive pulmonary disease (COPD) patient-reported outcome measurement.

METHODS

The discrimination and difficulty of the items from the modified patient-reported outcome scale for COPD (mCOPD-PRO) were analyzed using item response theory. Then the initial item, item selection method, ability estimation method, and stopping criteria were further set based on Concerto platform to form the CAT. Finally, the reliability and validity were validated.

RESULTS

The item discrimination ranged from 1.05 to 2.71, and the item difficulty ranged from - 3.08 to 3.65. The measurement reliability of the CAT ranged from 0.910 to 0.922 using random method, while that ranged from 0.910 to 0.924 using maximum Fisher information (MFI) method. The content validity was good. The correlation coefficient between theta of the CAT and COPD assessment test and modified Medical Research Council dyspnea scale scores using random method was 0.628 and 0.540 (P < 0.001; P < 0.001) respectively, while that using MFI method was 0.347 and 0.328 (P = 0.007; P = 0.010) respectively. About 11 items (reducing by 59.3%) on average were tested using random method, while about seven items (reducing by 74.1%) on average using MFI method. The correlation coefficient between theta of the CAT and mCOPD-PRO total scores using random method was 0.919 (P < 0.001), while that using MFI method was 0.760 (P < 0.001).

CONCLUSIONS

The comprehensive disease-specific CAT for COPD patient-reported outcome measurement is well developed with good psychometric properties, which can provide an efficient, accurate, and user-friendly measurement for patient-reported outcome of COPD.

摘要

背景

计算机化自适应测试（CAT）是一种减少时间、重复冗余和反应负担的有效方法，已被用于测量许多疾病的结果。本研究旨在开发和验证一种用于慢性阻塞性肺疾病（COPD）患者报告结局测量的全面疾病特异性 CAT。

方法

使用项目反应理论分析改良 COPD 患者报告结局量表（mCOPD-PRO）中的项目区分度和难度。然后，根据 Concerto 平台进一步设定初始项目、项目选择方法、能力估计方法和停止标准，以形成 CAT。最后，验证了可靠性和有效性。

结果

项目区分度范围为 1.05 至 2.71，项目难度范围为-3.08 至 3.65。使用随机方法时，CAT 的测量可靠性范围为 0.910 至 0.922，使用最大 Fisher 信息（MFI）方法时，测量可靠性范围为 0.910 至 0.924。内容效度良好。使用随机方法时，CAT 的 theta 与 COPD 评估测试和改良医学研究理事会呼吸困难量表评分之间的相关系数分别为 0.628 和 0.540（P<0.001；P<0.001），而使用 MFI 方法时，相关系数分别为 0.347 和 0.328（P=0.007；P=0.010）。使用随机方法平均测试约 11 项（减少 59.3%），使用 MFI 方法平均测试约 7 项（减少 74.1%）。使用随机方法时，CAT 的 theta 与 mCOPD-PRO 总分之间的相关系数为 0.919（P<0.001），而使用 MFI 方法时，相关系数为 0.760（P<0.001）。