Ganji Vidya, Sowganthikashri A, Taranikanti Madhuri, Kalpana M, Madhusudhan U, Gaur Archana, John Nitin A
Department of Physiology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
MBBS II Year Student, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, India.
J Family Med Prim Care. 2024 Aug;13(8):3005-3010. doi: 10.4103/jfmpc.jfmpc_1563_23. Epub 2024 Jul 26.
Cardiovascular diseases (CVD) account for approximately one-third of all deaths worldwide. The incidence of cardiovascular events such as myocardial infraction has been reported to be progressively increasing with age, especially with existing comorbidities such as hypertension, diabetes and obesity. Assessing arterial stiffness indices may serve as a screening tool in identification of population at risk of cardiovascular diseases and assist in implementation of preventive measures and early treatment in this population.
To measure and compare the arterial stiffness indices in healthy adults with diabetes, hypertension and obesity.
A total of 184 adults in the age group of 30-50 years were included in the study who were divided into 4 groups: Group I (n = 64) (diabetic), group II (n = 40) (hypertensives), group III (n = 40) (obese) and group IV (n = 40) (control). The arterial stiffness indices were measured by using a certified oscillometric device in all the participants.
The arterial stiffness indices were assessed by using a certified oscillometric device in all the participants. The mean values of right baPWV and left baPWV are found to be significantly higher in hypertensive subjects compared with obese, diabetic and healthy controls.
The pulse wave velocity, ASI and pulse pressure serve as independent predictors of cardiovascular mortality and outcomes in hypertension, diabetes and obesity as well as healthy individuals.
心血管疾病（CVD）约占全球所有死亡人数的三分之一。据报道，心肌梗死等心血管事件的发生率随年龄增长而逐渐上升，尤其是在患有高血压、糖尿病和肥胖症等现有合并症的人群中。评估动脉僵硬度指数可作为识别心血管疾病风险人群的筛查工具，并有助于对该人群实施预防措施和早期治疗。
测量并比较健康的糖尿病、高血压和肥胖成年人的动脉僵硬度指数。
本研究共纳入184名30至50岁的成年人，分为4组：第一组（n = 64）（糖尿病患者），第二组（n = 40）（高血压患者），第三组（n = 40）（肥胖者）和第四组（n = 40）（对照组）。所有参与者均使用经认证的示波装置测量动脉僵硬度指数。
所有参与者均使用经认证的示波装置评估动脉僵硬度指数。发现高血压患者的右肱踝脉搏波速度（baPWV）和左肱踝脉搏波速度的平均值明显高于肥胖者、糖尿病患者和健康对照组。
脉搏波速度、动脉僵硬度指数（ASI）和脉压是高血压、糖尿病、肥胖症患者以及健康个体心血管死亡率和预后的独立预测指标。
