Alhammami Qaed S
Radiology, Najran University, Najran, SAU.
Cureus. 2024 Aug 4;16(8):e66125. doi: 10.7759/cureus.66125. eCollection 2024 Aug.
This study aimed to compare the diagnostic accuracy of computed tomography (CT) and magnetic resonance imaging (MRI) in detecting metastases of colorectal cancer (CRC) in a hospital in Najran, Saudi Arabia. A total of 51 patients with CRC were included in the study. The radiological findings of metastatic lesions and the diagnostic accuracy measures of CT compared to MRI were analyzed. The results showed that CT had a false negative rate of 7.8%, a false positive rate of 7.8%, a true negative rate of 27.5%, and a true positive rate of 56.9% in detecting metastases. Diagnostic accuracy measures varied based on the number of metastatic lesions, with higher sensitivity observed for cases with fewer lesions. Gender, timing of imaging in relation to surgical intervention, and administration of nonsurgical therapy showed significant associations with diagnosis mismatch between CT and MRI. The site of metastases and the site of the primary tumor in the colon also demonstrated significant associations with diagnosis mismatch. The size of the largest metastasis detected by MRI was significantly associated with diagnosis mismatch. The overall diagnostic accuracy of CT in detecting any metastases, compared to MRI as the reference standard, was estimated to have a sensitivity of 87.8%, a specificity of 77.8%, a positive predictive value of 87.8%, and a negative predictive value of 77.8%. This study provides valuable insights into the comparative diagnostic performance of CT and MRI in detecting metastases of CRC, highlighting the importance of considering patient characteristics, disease outcome, and tumor characteristics in the interpretation of imaging results.
本研究旨在比较计算机断层扫描（CT）和磁共振成像（MRI）在沙特阿拉伯纳季兰一家医院检测结直肠癌（CRC）转移灶方面的诊断准确性。共有51例CRC患者纳入本研究。分析了转移灶的影像学表现以及CT与MRI相比的诊断准确性指标。结果显示，CT在检测转移灶时的假阴性率为7.8%，假阳性率为7.8%，真阴性率为27.5%，真阳性率为56.9%。诊断准确性指标因转移灶数量而异，转移灶较少的病例敏感性较高。性别、成像时间与手术干预的关系以及非手术治疗的实施与CT和MRI之间的诊断不匹配显著相关。转移灶部位和结肠原发肿瘤部位也与诊断不匹配显著相关。MRI检测到的最大转移灶大小与诊断不匹配显著相关。以MRI作为参考标准，CT检测任何转移灶的总体诊断准确性估计为：敏感性87.8%，特异性77.8%，阳性预测值87.8%，阴性预测值77.8%。本研究为CT和MRI在检测CRC转移灶方面的比较诊断性能提供了有价值的见解，强调了在解读影像结果时考虑患者特征、疾病转归和肿瘤特征的重要性。
