Alsareii Saeed, Almetrek Metrek Ali, Alshaiban Saleh Hussain, Alshahrani Reem S, Alshahrani Najla A, Atafi Thikra E, Almnjwami Rasan F, Oberi Imtenan A, Al-Ruwaili Reem H
Department of Surgery, College of Medicine, Najran University, Najran, SAU.
Department of Family Medicine, College of Medicine, Najran University, Najran, SAU.
Cureus. 2024 Aug 4;16(8):e66109. doi: 10.7759/cureus.66109. eCollection 2024 Aug.
Introduction Obesity affects over 650 million globally, with rising rates posing significant public health challenges, especially among Saudi Arabian women. Obesity correlates with menstrual irregularities and reproductive health issues such as polycystic ovary syndrome (PCOS). Bariatric surgery (BS), particularly laparoscopic sleeve gastrectomy (LSG), is increasingly used due to its safety and effectiveness in treating obesity-related conditions. This study explores LSG's impact on menstrual cycles and fertility in Saudi women, aiming to optimize patient care and understand surgical effects on hormonal dynamics and reproductive health. Methodology It is a cross-sectional design among Saudi women post-sleeve gastrectomy from December 2023 to May 2024. Variables included age, marital status, and region, with primary outcomes focusing on menstrual cycle changes post surgery. Results Our study includes 387 participants, and demographic characteristics showed a significant proportion aged 26-35 years (n=147, 38.0%) and 36-45 years (n=119, 30.7%), with the majority being married (n=230, 59.4%). Regional distribution highlighted the south as the most represented (n=139, 35.9%), followed by the central (n=74, 19.1%). About 30.2% (n=117) reported chronic conditions. Post surgery, 70.5% (n=273) experienced menstrual changes, with regular cycles being the most common (n=102, 26.3%). Logistic regression indicated younger age as a protective factor against menstrual changes (p=0.028), while pre-surgery menstrual irregularities significantly predicted post-surgery changes (p=0.002). Regional analysis showed no significant association between geographic location and post-surgery menstrual changes (p=0.140). Overall, quality of life post-surgery was rated highly by participants, with 70.8% (n=274) giving ratings of 4 or 5. Conclusion Our study highlights a high prevalence of post-sleeve gastrectomy menstrual changes, predominantly regular cycles. Younger age appears protective, while pre-existing menstrual irregularities strongly predict postoperative changes. Regional differences did not significantly influence outcomes. Overall, participants reported high satisfaction with their quality of life post surgery.
引言
肥胖在全球影响着超过6.5亿人，其发病率不断上升对公共卫生构成了重大挑战，在沙特阿拉伯女性中尤为如此。肥胖与月经不调和多囊卵巢综合征（PCOS）等生殖健康问题相关。减肥手术（BS），尤其是腹腔镜袖状胃切除术（LSG），因其在治疗肥胖相关病症方面的安全性和有效性而越来越多地被使用。本研究探讨LSG对沙特女性月经周期和生育能力的影响，旨在优化患者护理，并了解手术对激素动态和生殖健康的影响。
方法
这是一项对2023年12月至2024年5月接受袖状胃切除术后的沙特女性进行的横断面研究。变量包括年龄、婚姻状况和地区，主要结果集中在手术后月经周期的变化。
结果
我们的研究包括387名参与者，人口统计学特征显示，26至35岁的比例显著（n = 147，38.0%），36至45岁的比例为（n = 119，30.7%），大多数为已婚（n = 230，59.4%）。地区分布突出显示南部代表人数最多（n = 139，35.9%），其次是中部（n = 74，19.1%）。约30.2%（n = 117）报告患有慢性病。手术后，70.5%（n = 273）经历了月经变化，其中月经周期规律是最常见的（n = 102，26.3%）。逻辑回归表明，年龄较小是防止月经变化的保护因素（p = 0.028），而术前月经不规律显著预测术后变化（p = 0.002）。区域分析显示地理位置与术后月经变化之间无显著关联（p = 0.140）。总体而言，参与者对术后生活质量评价很高，70.8%（n = 274）给出了4或5分的评分。
结论
我们研究凸显了袖状胃切除术后月经变化的高发生率，主要为月经周期规律。年龄较小似乎具有保护作用，而术前存在的月经不规律强烈预测术后变化。地区差异对结果没有显著影响。总体而言，参与者报告对术后生活质量高度满意。
