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低剂量多组分药物作为预防和早期附加治疗儿童反复呼吸道感染的新方法:德尔菲共识。

A low-dose multicomponent medication as a new approach in prevention and early add-on treatment of recurrent respiratory infections in children: a Delphi Consensus.

机构信息

Pediatric Department, Hospital 'F. Del Ponte', University of Insubria, Varese, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2024 Aug;28(16):4156-4169. doi: 10.26355/eurrev_202408_36668.

Abstract

OBJECTIVE

Recurrent respiratory infections (RRIs) represent a demanding challenge in pediatricians' clinical practice. A previous Inter-Society Consensus defined criteria for identifying children with RRIs and assessed the available treatments, considering the evidence grade.

MATERIALS AND METHODS

The present Delphi consensus proposed a series of statements concerning the practical use of Citomix, a multicomponent low-dose medication. The participants should be primary care, private practice, and hospital/university pediatricians with extensive experience using this product to manage children with RRIs. One hundred twelve Italian pediatricians voted for the statements.

RESULTS

The agreement grade was high for all statements (ranging from 69.6% to 99.1%). The participants expressed their satisfaction with using this medication, which may represent a valuable and safe option for preventing and adding on treating children with RRIs. These statements reflected their personal opinions based on daily clinical practice.

CONCLUSIONS

The results of this Delphi consensus represented an input for further evidence-based studies highlighting the effectiveness of low-dose medications for both the prevention and treatment of RRIs.

摘要

目的

复发性呼吸道感染(RRIs)是儿科医生临床实践中的一个难题。先前的一项国际共识定义了识别 RRIs 儿童的标准,并评估了可用的治疗方法,同时考虑了证据等级。

材料和方法

本德尔菲共识提出了一系列关于 Citomix 实际应用的陈述,CitoMix 是一种多成分低剂量药物。参与者应为基层医疗、私人执业和医院/大学的儿科医生,他们在使用该产品管理 RRIs 儿童方面有丰富的经验。112 名意大利儿科医生对这些陈述进行了投票。

结果

所有陈述的一致性等级都很高(从 69.6%到 99.1%)。参与者对使用这种药物表示满意,这可能是预防和治疗 RRIs 儿童的一种有价值且安全的选择。这些陈述反映了他们基于日常临床实践的个人意见。

结论

本德尔菲共识的结果为进一步的基于证据的研究提供了依据,强调了低剂量药物在预防和治疗 RRIs 方面的有效性。

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