Kaur Arshdeep, Kumar Ranjeet
Department of Pharmacy Practice, ISF College of Pharmacy, Moga, (Punjab), India.
Curr Cardiol Rev. 2025;21(1):e1573403X323724. doi: 10.2174/011573403X323724240830075719.
Thirty percent of deaths worldwide are caused by cardiovascular disorders (CVDs). As per the WHO data, the number of fatalities due to CVDs is 17.9 million years, and it is projected to cause 22.2 million deaths by 2030. In terms of gender, women die from CVD at a rate of 51% compared to 42% for males. Most people use phytochemicals, a type of traditional medicine derived from plants, either in addition to or instead of commercially available medications to treat and prevent CVD. Phytochemicals are useful in lowering cardiovascular risks, especially for lowering blood cholesterol, lowering obesity-related factors, controlling blood sugar and the consequences of type 2 diabetes, controlling oxidative stress factors and inflammation, and preventing platelet aggregation. Medicinal plants that are widely known for treating CVD include ginseng, , ganoderma lucidum, gynostemma pentaphyllum, viridis amaranthus, etc. Plant sterol, flavonoids, polyphenols, sulphur compound and terpenoid are the active phytochemicals present in these plants. The aim of this article is to cover more and more drugs that are used for cardiovascular diseases. In this article, we will learn about the use of different herbal drugs, mechanism of action, phytochemical compounds, side effects, etc. However, more research is required to comprehend the process and particular phytochemicals found in plants that treat CVD.
全球30%的死亡是由心血管疾病(CVD)导致的。根据世界卫生组织的数据,因心血管疾病死亡的人数达1790万,预计到2030年将导致2220万人死亡。在性别方面,女性死于心血管疾病的比例为51%,而男性为42%。大多数人使用植物化学物质(一种源自植物的传统药物)来治疗和预防心血管疾病,要么是在使用市售药物的基础上,要么是取而代之。植物化学物质有助于降低心血管疾病风险,特别是在降低血液胆固醇、降低与肥胖相关的因素、控制血糖和2型糖尿病的后果、控制氧化应激因素和炎症以及防止血小板聚集方面。广泛用于治疗心血管疾病的药用植物包括人参、灵芝、绞股蓝、绿穗苋等。植物甾醇、黄酮类化合物、多酚、硫化合物和萜类化合物是这些植物中存在的活性植物化学物质。本文的目的是涵盖越来越多用于治疗心血管疾病的药物。在本文中,我们将了解不同草药的用途、作用机制、植物化学成分、副作用等。然而,需要更多的研究来了解治疗心血管疾病的植物中的过程和特定植物化学物质。