Schwartz-Arad Surgical Center, 15 Habarzel St, Tel Aviv, Israel.
Int J Implant Dent. 2024 Sep 4;10(1):40. doi: 10.1186/s40729-024-00556-9.
The present study evaluated osteopenia (OPN) and osteoporosis (OP) as risk factors for dental implant failure and repeat failure.
We performed a retrospective study on over 100 randomly selected patients per analysis to determine the effect of health status, smoking status, sex, implant location and operative conditions on first and second (re-implantation) implant survival. Analyses were conducted first using chi-squared test, followed by multiple logistic regression for significant variables.
In the cohort examining the effect of myriad risk factors on second implant survival, it was found that OPN and OP greatly impacted implant survival, wherein patients with osteoporosis or osteopenia had significantly more implant failures (p = 0.0353). Sex and operative conditions had no effect on implant survival, while implant location showed a notable effect wherein significantly more failures occurred in the maxilla vs mandible (p = 0.0299). Upon finding that OPN and OP have a significant effect on second implant survival, we conducted an additional study focusing on the impact of health status. Based on the multiple logistical regression analysis, we found that OPN and OP are the most significant factor in first implant survival (p = 0.0065), followed by diabetes (p = 0.0297). Importantly, it was observed that early implant failure is also significantly correlated with osteoporosis (p = 0.0044).
We show here a marked relationship in which the risk of first and second implant failure are significantly higher in patients with osteoporosis and osteopenia.
本研究评估了骨质疏松症(OPN)和骨质疏松症(OP)作为牙种植体失败和重复失败的风险因素。
我们对每 100 名随机选择的患者进行了回顾性研究,以确定健康状况、吸烟状况、性别、种植体位置和手术条件对首次和第二次(再植入)种植体存活的影响。首先使用卡方检验进行分析,然后对显著变量进行多因素逻辑回归分析。
在研究众多危险因素对第二次种植体存活影响的队列中,发现 OPN 和 OP 对种植体存活有很大影响,患有骨质疏松症或骨质疏松症的患者种植体失败明显更多(p = 0.0353)。性别和手术条件对种植体存活没有影响,而种植体位置显示出明显的影响,上颌骨的失败明显多于下颌骨(p = 0.0299)。发现 OPN 和 OP 对第二次种植体存活有显著影响后,我们进行了一项额外的研究,重点研究健康状况的影响。基于多因素逻辑回归分析,我们发现 OPN 和 OP 是首次种植体存活的最重要因素(p = 0.0065),其次是糖尿病(p = 0.0297)。重要的是,观察到早期种植体失败与骨质疏松症也显著相关(p = 0.0044)。
我们在这里表明,骨质疏松症和骨质疏松症患者的第一次和第二次种植体失败风险明显更高。