BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Wiad Lek. 2024;77(8):1627-1632. doi: 10.36740/WLek202408114.
Coronavirus disease (COVID-19), which broke out in China and caused a devastating pandemic worldwide, is associated with a significantly increased risk of thrombotic complications, especially pulmonary embolism. During the COVID-19 pandemic, investigations have reported a high incidence of venous thromboembolic (VTE) events in hospitalized patients with COVID-19, often despite thromboprophylaxis. Current recommendations for thromboprophylaxis are based on randomized clinical trials, which usually exclude patients at а potentially high risk of hemorrhagic complications. This category includes patients with liver cirrhosis complicated by variceal bleeding, thrombocytopenia, and coagulopathy. We present three patients who suffered severe covid pneumonia and were hospitalized with acute variceal bleeding, who developed fatal thromboembolic complications in the postoperative period.
冠状病毒病(COVID-19)在中国爆发并在全球造成毁灭性大流行,与血栓并发症的风险显著增加有关,尤其是肺栓塞。在 COVID-19 大流行期间,研究报告称 COVID-19 住院患者静脉血栓栓塞(VTE)事件的发生率很高,尽管进行了血栓预防。目前的血栓预防建议是基于随机临床试验,这些试验通常排除了有潜在出血并发症高风险的患者。这一类包括伴有静脉曲张出血、血小板减少症和凝血功能障碍的肝硬化患者。我们介绍了 3 名患有严重新冠肺炎的患者,他们因急性静脉曲张出血住院,在术后发生了致命的血栓栓塞并发症。