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癌症和脊髓损伤患者的自主反射障碍:病例系列研究。

Autonomic dysreflexia in patients with cancer and spinal cord injury: a case series.

机构信息

Rehabilitation Medicine Service, Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

出版信息

Spinal Cord Ser Cases. 2024 Sep 4;10(1):66. doi: 10.1038/s41394-024-00678-7.

Abstract

INTRODUCTION

Autonomic dysreflexia (AD) is a potentially life-threatening syndrome that can occur in patients with traumatic injury to the spinal cord; however, it has not been well described in patients with non-traumatic spinal cord injury (SCI) from cancer and its treatments.

CASE PRESENTATION

We report four cases of autonomic dysreflexia secondary to primary spinal cord tumors and metastatic disease to the spine, and as sequela to cancer treatment. The clinical characteristics, diagnostic considerations, and therapeutic strategies used to mitigate the symptoms are discussed.

DISCUSSION

The case series shows that AD is a rare but important condition to consider among patients with cancer-related SCI. There is a need for close monitoring and early identification of this syndrome in this population. Therapeutic strategies are available to mitigate these symptoms and risks of complications.

摘要

简介

自主反射异常(AD)是一种可能危及生命的综合征,可发生在脊髓创伤的患者中;然而,在由癌症及其治疗引起的非外伤性脊髓损伤(SCI)患者中,尚未对其进行很好的描述。

病例介绍

我们报告了 4 例继发于原发性脊髓肿瘤和脊柱转移瘤,以及癌症治疗后并发症的自主反射异常病例。讨论了用于缓解症状的临床特征、诊断注意事项和治疗策略。

讨论

该病例系列表明,AD 是癌症相关 SCI 患者中一种罕见但重要的需要考虑的情况。在这一人群中,需要密切监测和早期识别这种综合征。有治疗策略可减轻这些症状和并发症的风险。

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