Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Department of Orthopaedic Surgery, Kyushu Rosai Hospital, Fukuoka, Japan.
Sci Rep. 2024 Sep 4;14(1):20627. doi: 10.1038/s41598-024-71830-4.
The coronavirus disease (COVID-19) pandemic negatively affected the diagnosis and treatment of several cancer types. However, this pandemic's exact impact and extent on bone and soft tissue sarcomas need to be clarified. We aimed to investigate the effect of the COVID-19 pandemic and emergency declaration by the local government on consultation behavior and clinical stage at diagnosis of bone and soft tissue sarcoma. A total of 403 patients diagnosed with bone and soft tissue sarcoma who initially visited three sarcoma treatment hospitals between January 2018 and December 2021 were included. The monthly number of newly diagnosed soft tissue sarcoma patients was reduced by 25%, and the proportion of soft tissue patients with stage IV disease at diagnosis significantly increased by 9% during the COVID-19 pandemic compared to before the COVID-19 pandemic. Furthermore, the monthly number of new primary bone and soft tissue sarcoma patients significantly decreased by 43% during the state of emergency declaration. The COVID-19 pandemic had a negative impact on soft tissue sarcoma patients' consultation behavior and increased the proportion of advanced-stage patients at initial diagnosis. An emergency declaration by the local government also negatively affected primary bone and soft tissue sarcoma patients' consultation behavior.
冠状病毒病 (COVID-19) 大流行对几种癌症的诊断和治疗产生了负面影响。然而，需要明确 COVID-19 大流行对骨和软组织肉瘤的确切影响和程度。我们旨在研究 COVID-19 大流行和当地政府宣布紧急状态对骨和软组织肉瘤的咨询行为和诊断时临床分期的影响。共纳入了 2018 年 1 月至 2021 年 12 月期间首次访问三家肉瘤治疗医院的 403 名骨和软组织肉瘤患者。COVID-19 大流行期间，新诊断的软组织肉瘤患者每月数量减少了 25%，诊断时 IV 期疾病的软组织患者比例显著增加了 9%。此外，在宣布紧急状态期间，新原发性骨和软组织肉瘤患者每月数量显著减少了 43%。COVID-19 大流行对软组织肉瘤患者的咨询行为产生了负面影响，并增加了初始诊断时晚期患者的比例。当地政府宣布紧急状态也对原发性骨和软组织肉瘤患者的咨询行为产生了负面影响。
