Center of Pharmaceutical Engineering and Technology, Harbin University of Commerce, Harbin 150076, China.
Center of Pharmaceutical Engineering and Technology, Harbin University of Commerce, Harbin 150076, China.
Ultrason Sonochem. 2024 Nov;110:107056. doi: 10.1016/j.ultsonch.2024.107056. Epub 2024 Sep 1.
Based on sonochemistry, green synthesis methods play an important role in the development of nanomaterials. In this work, a novel chitosan modified MnMoO/g-CN (MnMoO/g-CN/CHIT) was developed using ultrasonic cell disruptor (500 W, 30 kHz) for ultra-sensitive electrochemical detection of tinidazole (TNZ) in the environment. The morphology and surface properties of the synthesized MnMoO/g-CN/CHIT electrode were characterized using X-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM) and transmission electron microscope (TEM). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques were utilized to assess the electrochemical performance of TNZ. The results indicate that the electrochemical detection performance of TNZ is highly efficient, with a detection limit (LOD) of 3.78 nM, sensitivity of 1.320 µA·µM·cm, and a detection range of 0.1-200 μM. Additionally, the prepared electrode exhibits excellent selectivity, desirable anti-interference capability, and decent stability. MnMoO/g-CN/CHIT can be successfully employed to detect TNZ in both the Songhua River and tap water, achieving good recovery rates within the range of 93.0 % to 106.6 %. Consequently, MnMoO/g-CN/CHIT's simple synthesis might provide a new electrode for the sensitive, repeatable, and selective measurement of TNZ in real-time applications. Using the MnMoO/g-CN/CHIT electrode can effectively monitor and detect the concentration of TNZ in environmental water, guiding the sewage treatment process and reducing the pollution level of antibiotics in the water environment.
基于声化学，绿色合成方法在纳米材料的发展中起着重要作用。在这项工作中，使用超声细胞破碎仪（500 W，30 kHz）开发了一种新型壳聚糖修饰的 MnMoO/g-CN（MnMoO/g-CN/CHIT），用于环境中替硝唑（TNZ）的超灵敏电化学检测。采用 X 射线衍射（XRD）、傅里叶变换红外光谱（FT-IR）、扫描电子显微镜（SEM）和透射电子显微镜（TEM）对合成的 MnMoO/g-CN/CHIT 电极的形貌和表面性质进行了表征。循环伏安法（CV）和差分脉冲伏安法（DPV）技术用于评估 TNZ 的电化学性能。结果表明，TNZ 的电化学检测性能高效，检测限（LOD）为 3.78 nM，灵敏度为 1.320 µA·µM·cm，检测范围为 0.1-200 µM。此外，所制备的电极表现出优异的选择性、理想的抗干扰能力和良好的稳定性。MnMoO/g-CN/CHIT 可成功用于松花江和自来水的 TNZ 检测，在 93.0%至 106.6%的范围内实现了良好的回收率。因此，MnMoO/g-CN/CHIT 的简单合成可能为实时应用中 TNZ 的灵敏、可重复和选择性测量提供新的电极。使用 MnMoO/g-CN/CHIT 电极可以有效地监测和检测环境水中 TNZ 的浓度，指导污水处理过程，降低水环境中抗生素的污染水平。
