Editorial overview: Breaking boundaries: new frontiers in chromatin regulation for cancer therapy.
作者信息
Shilatifard Ali, Lauberth Shannon M
机构信息
Simpson Querrey Institute for Epigenetics and Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
出版信息
Curr Opin Genet Dev. 2024 Oct;88:102255. doi: 10.1016/j.gde.2024.102255. Epub 2024 Sep 3.
Abstract
摘要
相似文献
1
Editorial overview: Breaking boundaries: new frontiers in chromatin regulation for cancer therapy.社论综述：突破界限：癌症治疗中染色质调控的新前沿
Curr Opin Genet Dev. 2024 Oct;88:102255. doi: 10.1016/j.gde.2024.102255. Epub 2024 Sep 3.
2
Chromatin engineering offers an opportunity to advance epigenetic cancer therapy.染色质工程为推进表观遗传癌症治疗提供了一个契机。
Nat Struct Mol Biol. 2019 Oct;26(10):842-845. doi: 10.1038/s41594-019-0299-6.
3
The epigenetics of cancer: from non-coding RNAs to chromatin and beyond.癌症表观遗传学：从非编码RNA到染色质及其他
Brief Funct Genomics. 2013 May;12(3):161-3. doi: 10.1093/bfgp/elt020.
4
Cancer and epigenesis: a developmental perspective.癌症与表观遗传学：发育视角
Adv Pediatr. 2003;50:59-80.
5
Epigenetics: Chromatin marks the spot.表观遗传学：染色质标记位点。
Nat Rev Cancer. 2015 Apr;15(4):196-7. doi: 10.1038/nrc3934. Epub 2015 Mar 19.
6
Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies.表观遗传和染色质修饰剂作为血液系统恶性肿瘤的靶向治疗
J Clin Oncol. 2005 Jun 10;23(17):3971-93. doi: 10.1200/JCO.2005.16.600. Epub 2005 May 16.
7
Epigenetic information in chromatin and cancer.染色质和癌症中的表观遗传学信息。
Eur J Cancer. 2009 Sep;45 Suppl 1:442-4. doi: 10.1016/S0959-8049(09)70082-6.
8
Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.癌症基因组的三维无序与远距离遗传和表观遗传改变同时发生。
Genome Res. 2016 Jun;26(6):719-31. doi: 10.1101/gr.201517.115. Epub 2016 Apr 6.
9
The impact of cellular metabolism on chromatin dynamics and epigenetics.细胞代谢对染色质动力学和表观遗传学的影响。
Nat Cell Biol. 2017 Nov;19(11):1298-1306. doi: 10.1038/ncb3629. Epub 2017 Oct 23.
10
Chromatin dependencies in cancer and inflammation.染色质在癌症和炎症中的依赖性。
Nat Rev Mol Cell Biol. 2018 Apr;19(4):245-261. doi: 10.1038/nrm.2017.113. Epub 2017 Nov 29.
本文引用的文献
1
Dysregulation of transcriptional condensates in human disease: mechanisms, biological functions, and open questions.人类疾病中转录凝聚物的失调：机制、生物学功能和未解决的问题。
Curr Opin Genet Dev. 2024 Jun;86:102203. doi: 10.1016/j.gde.2024.102203. Epub 2024 May 23.
2
Hijacked enhancer-promoter and silencer-promoter loops in cancer.癌症中的劫持增强子-启动子和沉默子-启动子环。
Curr Opin Genet Dev. 2024 Jun;86:102199. doi: 10.1016/j.gde.2024.102199. Epub 2024 Apr 25.
3
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia.染色质和异常增强子活性在 KMT2A 重排的急性淋巴细胞白血病中。
Curr Opin Genet Dev. 2024 Jun;86:102191. doi: 10.1016/j.gde.2024.102191. Epub 2024 Apr 4.
4
Therapeutic targeting of BET bromodomain and other epigenetic acetylrecognition domain-containing factors.靶向治疗 BET 溴结构域和其他包含表观遗传乙酰化识别结构域的因子。
Curr Opin Genet Dev. 2024 Jun;86:102181. doi: 10.1016/j.gde.2024.102181. Epub 2024 Apr 2.
5
Safeguarding the epigenome through the cell cycle: a multitasking game.通过细胞周期保护表观基因组：一项多任务游戏。
Curr Opin Genet Dev. 2024 Apr;85:102161. doi: 10.1016/j.gde.2024.102161. Epub 2024 Mar 5.
6
Somatic hypermutation mechanisms during lymphomagenesis and transformation.在淋巴瘤发生和转化过程中的体细胞超突变机制。
Curr Opin Genet Dev. 2024 Apr;85:102165. doi: 10.1016/j.gde.2024.102165. Epub 2024 Feb 29.
7
Hexasomal particles: consequence or also consequential?六联体颗粒：结果还是也有因果关系？
Curr Opin Genet Dev. 2024 Apr;85:102163. doi: 10.1016/j.gde.2024.102163. Epub 2024 Feb 26.
8
Approaches to probe and perturb long noncoding RNA functions in diseases.探讨和干扰疾病中长链非编码 RNA 功能的方法。
Curr Opin Genet Dev. 2024 Apr;85:102158. doi: 10.1016/j.gde.2024.102158. Epub 2024 Feb 26.
9
Therapeutic index of targeting select chromatin complexes in human cancer patients.靶向人类癌症患者特定染色质复合物的治疗指数。
Curr Opin Genet Dev. 2024 Apr;85:102162. doi: 10.1016/j.gde.2024.102162. Epub 2024 Feb 24.
10
Cohesin regulation and roles in chromosome structure and function.黏连蛋白的调控及其在染色体结构和功能中的作用。
Curr Opin Genet Dev. 2024 Apr;85:102159. doi: 10.1016/j.gde.2024.102159. Epub 2024 Feb 20.
Zotero 插件