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通过蛋白质工程推动可持续生物技术发展。

Advancing sustainable biotechnology through protein engineering.

机构信息

McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.

McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA; Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, USA.

出版信息

Trends Biochem Sci. 2024 Nov;49(11):955-968. doi: 10.1016/j.tibs.2024.07.006. Epub 2024 Sep 3.

DOI:10.1016/j.tibs.2024.07.006
PMID:39232879
Abstract

The push for industrial sustainability benefits from the use of enzymes as a replacement for traditional chemistry. Biological catalysts, especially those that have been engineered for increased activity, stability, or novel function, and are often greener than alternative chemical approaches. This Review highlights the role of engineered enzymes (and identifies directions for further engineering efforts) in the application areas of greenhouse gas sequestration, fuel production, bioremediation, and degradation of plastic wastes.

摘要

推动工业可持续发展得益于将酶作为传统化学物质的替代品。生物催化剂,尤其是那些经过设计以提高活性、稳定性或新功能的生物催化剂,通常比替代化学方法更为环保。这篇综述强调了工程酶(并确定了进一步工程努力的方向)在温室气体固存、燃料生产、生物修复以及塑料废物降解等应用领域中的作用。

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