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微血管减压术治疗非动脉瘤性神经血管冲突所致动眼神经麻痹:5例报告及文献复习

Microvascular Decompression for Oculomotor Nerve Palsy Due to Nonaneurysmal Neurovaslur Conflict: 5 Cases Report and Literature Review.

作者信息

Zhao Hua, Wang Baimiao, Tang Yinda, Li Shiting

机构信息

Neurosurgery Department, Xinhua hospital affiliated to Shanghai jiaotong University School of Medicine, Shanghai, China.

Neurosurgery Department, Xinhua hospital affiliated to Shanghai jiaotong University School of Medicine, Shanghai, China.

出版信息

World Neurosurg. 2024 Nov;191:e356-e364. doi: 10.1016/j.wneu.2024.08.130. Epub 2024 Sep 2.

Abstract

BACKGROUND

Oculomotor nerve palsy (ONP) is frequently caused by aneurysm compression and diabetes mellitus. However, nonaneurysmal compression (nAVC) of the oculomotor nerve is a condition rarely reported in the literature. Cases treated with microvascular decompression (MVD) for nAVC-induced ONP (nAVC-ONP) are exceptionally rare.

METHODS

Between October 2022 and October 2023, we performed MVD surgery on 5 patients diagnosed with nAVC-ONP. The clinical symptoms, imaging characteristics, and intraoperative findings of these patients were reviewed and analyzed using a self-developed evaluation scale (S-T Evaluation Scale) to guide diagnosis and corresponding treatment plans.

RESULTS

All patients underwent MVDs and demonstrated favorable recovery and a good prognosis. No postoperative complications occurred in any of the patients. The superior cerebellar artery and posterior cerebral artery were common offending vessels in these cases.

CONCLUSIONS

Neurovascular conflict has been proposed as another possible cause of ONP in a limited number of cases. Based on our findings, MVD is a potentially effective solution for patients experiencing oculomotor nerve palsy resulting from nonaneurysmal neurovascular conflicts. It holds great promise for significantly alleviating symptoms and improving overall quality of life.

摘要

背景

动眼神经麻痹(ONP)常由动脉瘤压迫和糖尿病引起。然而,动眼神经的非动脉瘤性压迫(nAVC)在文献中鲜有报道。因nAVC导致的ONP(nAVC-ONP)采用微血管减压术(MVD)治疗的病例极为罕见。

方法

2022年10月至2023年10月期间,我们对5例诊断为nAVC-ONP的患者进行了MVD手术。使用自行研制的评估量表(S-T评估量表)对这些患者的临床症状、影像学特征和术中发现进行回顾和分析,以指导诊断和相应的治疗方案。

结果

所有患者均接受了MVD手术,恢复良好,预后良好。所有患者均未发生术后并发症。在这些病例中,小脑上动脉和大脑后动脉是常见的责任血管。

结论

在少数病例中,神经血管冲突被认为是ONP的另一个可能原因。根据我们的研究结果,MVD对于因非动脉瘤性神经血管冲突导致动眼神经麻痹的患者是一种潜在有效的解决方案。它在显著缓解症状和提高整体生活质量方面具有很大的前景。

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