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水凝胶敷料联合多学科治疗小儿重度烧伤:1 例成功治愈及预防增生性瘢痕的病例报告

Hydrogel-Based Dressings and Multidisciplinary Care in Severe Pediatric Burns: A Case Report of Successful Healing and Hypertrophic Scar Prevention.

机构信息

Department of Plastic Surgery, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.

Department of Medicine, Fakeeh College for Medical Sciences, Jeddah, Saudi Arabia.

出版信息

Am J Case Rep. 2024 Sep 5;25:e944021. doi: 10.12659/AJCR.944021.

DOI:10.12659/AJCR.944021
PMID:39233392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11384673/
Abstract

BACKGROUND Pediatric burn injuries are a global health concern, particularly in infants and toddlers, who face increased risks owing to their higher water content. Despite substantial medical treatment, the mortality rates remain challenging, especially in severe cases. This study explored non-surgical interventions for pediatric burn injuries, aiming to enhance care and alleviate the burden on affected children. CASE REPORT A 16-month-old boy with 30% mixed second- and third-degree burns presented with a scald injury. Initial measures included dressing and analgesia. The Plastic Surgery team led the treatment. Upon admission, the patient experienced convulsions due to hyponatremia in the burn unit and was subsequently transferred to the Pediatric Intensive Care Unit (PICU). Burn care management included the use of hyaluronic acid and occupational therapy. Scheduled dressing changes, including the use of glycerin-based dressings, resulted in satisfactory wound healing. Split skin grafting from the right thigh was performed to prevent elbow joint contracture. Preventive measures against hypertrophic scarring were also implemented. The patient was discharged after follow-up appointments. Consent for publication of case details and photographs was obtained from the patient's father. CONCLUSIONS The presented non-surgical approach, incorporating hyaluronic acid, Bactigras, Elasto-Gel, and a multidisciplinary team, can effectively treat mixed partial- and full-thickness burn injuries in pediatric populations. Split-thickness grafts may be required in functional areas. Therefore, a comprehensive management strategy that considers tissue damage, electrolyte balance, and infection is crucial. This report underscores the importance of meticulous assessment and correction of overall patient condition, especially in pediatric cases of electrolyte imbalance.

摘要

背景

儿科烧伤是全球关注的健康问题,特别是婴儿和幼儿,由于其较高的水分含量,面临更高的风险。尽管进行了大量的医疗治疗,死亡率仍然具有挑战性,尤其是在严重的情况下。本研究探讨了儿科烧伤的非手术干预措施,旨在加强护理并减轻受影响儿童的负担。

病例报告

一名 16 个月大的男孩因热水烫伤导致全身 30%混合二度和三度烧伤。初步措施包括包扎和止痛。整形外科团队主导治疗。入院时,患儿因烧伤病房中的低钠血症出现抽搐,随后被转至儿科重症监护病房(PICU)。烧伤治疗管理包括使用透明质酸和职业治疗。定期进行换药,包括使用甘油基敷料,伤口愈合情况良好。从右大腿取皮片进行游离植皮,以预防肘关节挛缩。还采取了预防增生性瘢痕的措施。患儿在随访预约后出院。已从患儿父亲处获得发布病例详情和照片的同意。

结论

本研究提出的非手术方法,包括使用透明质酸、Bactigras、Elasto-Gel 和多学科团队,可以有效治疗儿科人群中的混合部分和全层烧伤。在功能区域可能需要进行皮肤移植。因此,考虑组织损伤、电解质平衡和感染的综合管理策略至关重要。本报告强调了对整体患者状况进行细致评估和纠正的重要性,尤其是在儿科电解质失衡的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/c43469171bce/amjcaserep-25-e944021-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/8134be90eb36/amjcaserep-25-e944021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/052d7780bd73/amjcaserep-25-e944021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/f9976106f869/amjcaserep-25-e944021-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/29aa4396982d/amjcaserep-25-e944021-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/c43469171bce/amjcaserep-25-e944021-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/8134be90eb36/amjcaserep-25-e944021-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/052d7780bd73/amjcaserep-25-e944021-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/f9976106f869/amjcaserep-25-e944021-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/29aa4396982d/amjcaserep-25-e944021-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7f/11384673/c43469171bce/amjcaserep-25-e944021-g005.jpg

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本文引用的文献

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Injectable hydrogel based on silk fibroin/carboxymethyl cellulose/agarose containing polydopamine functionalized graphene oxide with conductivity, hemostasis, antibacterial, and anti-oxidant properties for full-thickness burn healing.基于丝素蛋白/羧甲基纤维素/琼脂糖并含有聚多巴胺功能化氧化石墨烯的可注射水凝胶,具有导电性、止血性、抗菌性和抗氧化性,用于全层烧伤愈合。
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