Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia, USA.
Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, Indiana, USA.
Magn Reson Med. 2025 Jan;93(1):199-212. doi: 10.1002/mrm.30266. Epub 2024 Sep 4.
To develop an efficient navigator-based motion and temporal B-shift correction technique for 3D multi-echo gradient-echo (ME-GRE) MRI for quantitative susceptibility mapping (QSM) and mapping.
A dual-echo 3D stack-of-spiral navigator was designed to interleave with the Cartesian multi-echo gradient-echo acquisitions, allowing the acquisition of both low-echo and high-echo time signals. We additionally designed a novel conjugate phase-based reconstruction method for the joint correction of motion and temporal B shifts. We performed numerical simulation, phantom scans, and in vivo human scans to assess the performance of the methods.
Numerical simulation and human brain scans demonstrated that the proposed technique successfully corrected artifacts induced by both head motions and temporal B changes. Efficient B-change correction with conjugate-phase reconstruction can be performed on fewer than 10 clustered k-space segments. In vivo scans showed that combining temporal B correction with motion correction further reduced artifacts and improved image quality in both and QSM images.
Our proposed approach of using 3D spiral navigators and a novel conjugate-phase reconstruction method can improve susceptibility-related measurements using MR.
开发一种基于导航的高效运动和时间 B 移校正技术，用于 3D 多回波梯度回波（ME-GRE）MRI 的定量磁化率映射（QSM）和映射。
设计了双回波 3D 螺旋堆叠导航器，与笛卡尔多回波梯度回波采集交错，允许采集低回波和高回波时间信号。我们还设计了一种新的基于共轭相位的重建方法，用于联合校正运动和时间 B 移位。我们进行了数值模拟、体模扫描和人体内部扫描，以评估这些方法的性能。
数值模拟和人脑扫描表明，所提出的技术成功校正了由头部运动和时间 B 变化引起的伪影。使用共轭相位重建可以在少于 10 个聚类的 k 空间段上进行有效的 B 变化校正。体内扫描表明，在运动校正的基础上结合时间 B 校正，进一步减少了伪影，并提高了和 QSM 图像的图像质量。
我们提出的使用 3D 螺旋导航器和一种新的共轭相位重建方法的方法可以改善使用磁共振进行与磁化率相关的测量。
