Farahat A Rahman, Roohi Mahera
Department of Pathology, Blood Bank and Laboratory Medicine, King Hamad University Hospital, Manama, BHR.
Cureus. 2024 Aug 5;16(8):e66167. doi: 10.7759/cureus.66167. eCollection 2024 Aug.
Amyloid goiter (AG) is a condition in which amyloid protein builds up in the thyroid gland. Patients with such a condition tend to have thyroid tissue that is extensively involved by amyloid; however, patients are usually euthyroid. Systemic amyloidosis is one of the conditions that may cause damage to the kidneys or worsen the condition of kidney failure in patients with ongoing chronic kidney disease as amyloid proteins can deposit in a variety of tissues including kidneys. Thyroid goiter can rarely be the first confirmed place to be involved with amyloidosis. We present the case of a 57-year-old female with AG who had a history of renal failure.
淀粉样变甲状腺肿(AG)是一种淀粉样蛋白在甲状腺中积聚的病症。患有这种病症的患者往往甲状腺组织广泛被淀粉样蛋白累及;然而,患者通常甲状腺功能正常。系统性淀粉样变是可能损害肾脏或使慢性肾脏病患者肾衰竭病情恶化的病症之一,因为淀粉样蛋白可沉积于包括肾脏在内的多种组织。甲状腺肿很少会是首个被确诊发生淀粉样变的部位。我们报告一例57岁患AG且有肾衰竭病史的女性病例。