Muqeet Muhammad Abdul, Riaz Muhammad Uzair, Qaisar Summaiya, Ahmad Naveed, Nisar Amna, Rizvi Syeda Sameen Zehra
Department of Prosthodontics, Dental College, Heavy Industries Taxila Education City Institute of Medical Sciences (HITEC-IMS), Taxilla, PAK.
Department of Prosthodontics, De'Montmorency College of Dentistry, Lahore, PAK.
Cureus. 2024 Aug 5;16(8):e66208. doi: 10.7759/cureus.66208. eCollection 2024 Aug.
There is growing interest in the relationship between prosthodontic therapies and outcomes related to systemic health, particularly respiratory infections. Respiratory infections are a leading cause of global morbidity and mortality, particularly among vulnerable populations such as immunocompromised individuals. The World Health Organization reports that lower respiratory infections are among the top causes of death worldwide, underscoring the importance of understanding their potential link to prosthodontic procedures. Dental operations, such as prosthodontic therapies, may alter the mouth flora and thus affect respiratory health.
This research aimed to investigate the relationship between prosthodontic procedures and chest infections.
This research was an observational prospective cohort study conducted from January 2023 to December 2023 at the Pakistan Institute of Medical Sciences (PIMS) located in Islamabad, Pakistan. One hundred thirty individuals in the cohort, who were at least 18 years old, had a range of prosthodontic procedures, such as total edentulous solutions and tooth restoration. Electronic health data were used for participant selection to minimize selection bias and guarantee diverse representation. Comprehensive evaluations of cardiovascular health, immunological state, pulmonary function, and medical histories were all part of the data-gathering process. Structured questionnaires and interviews were also used to get patient feedback. Using SPSS Statistics software (version 27; IBM Corp., Armonk, NY), statistical analysis was performed to examine the relationships between prosthodontic treatments and chest infections using descriptive statistics and logistic regression.
PIMS hosted 130 participants in this research, which found that 29 patients, or 22% of the total, had chest infections after surgery. Chest infection rates were 15.15% (five out of 33) in the 18-39 age group, 21.21% (14 out of 66) in the 40-59 age group, and 32.26% (10 out of 31) in the 60+ age group, according to age-specific analysis. Complete edentulous solutions (38 cases, 29.23%) and tooth restoration (55 cases, 42.31%) were the most frequently performed procedures. Compared to tooth restoration (n=15; 55.17%), complete edentulous solutions (n=8; 27.59%) had increased infection risks, according to logistic regression. Following prosthodontic procedures, respiratory health measures improved: respiratory rate dropped to 17.8/min, oxygen saturation rose to 98.1%, and frequency of coughing fell to 1.9/day.
This research highlights the need for careful post-operative respiratory surveillance by elucidating the strong associations between prosthodontic procedures and chest infections.
人们对口腔修复治疗与全身健康相关结果之间的关系，尤其是与呼吸道感染的关系越来越感兴趣。呼吸道感染是全球发病和死亡的主要原因，在免疫功能低下等弱势群体中尤为如此。世界卫生组织报告称，下呼吸道感染是全球主要死因之一，这凸显了了解其与口腔修复程序潜在联系的重要性。诸如口腔修复治疗等牙科手术可能会改变口腔菌群，从而影响呼吸道健康。
本研究旨在调查口腔修复程序与胸部感染之间的关系。
本研究是一项观察性前瞻性队列研究，于2023年1月至2023年12月在位于巴基斯坦伊斯兰堡的巴基斯坦医学科学研究所（PIMS）进行。该队列中有130名个体，年龄至少18岁，接受了一系列口腔修复程序，如全口无牙解决方案和牙齿修复。使用电子健康数据进行参与者选择，以尽量减少选择偏倚并确保具有多样化的代表性。心血管健康、免疫状态、肺功能和病史的综合评估都是数据收集过程的一部分。还使用结构化问卷和访谈来获取患者反馈。使用SPSS统计软件（版本27；IBM公司，纽约州阿蒙克），通过描述性统计和逻辑回归进行统计分析，以检查口腔修复治疗与胸部感染之间的关系。
PIMS在本研究中接待了130名参与者，研究发现29名患者（占总数的22%）术后发生了胸部感染。按年龄组分析，18 - 39岁年龄组的胸部感染率为15.15%（33人中有5人），40 - 59岁年龄组为21.21%（66人中有14人），60岁及以上年龄组为32.26%（31人中有10人）。全口无牙解决方案（38例，29.23%）和牙齿修复（55例，42.31%）是最常进行的程序。逻辑回归分析显示，与牙齿修复（n = 15；55.17%）相比，全口无牙解决方案（n = 8；27.59%）的感染风险增加。口腔修复程序后，呼吸健康指标有所改善：呼吸频率降至17.8次/分钟，血氧饱和度升至98.1%，咳嗽频率降至1.9次/天。
本研究通过阐明口腔修复程序与胸部感染之间的紧密关联，强调了术后进行仔细呼吸监测的必要性。
