Zhu Wenli, Zhang Yan, Wang Linda Dong-Ling, Li Jiajia, Hou Sicong
School of Public Health, Yangzhou University, Yangzhou, Jiangsu Province, China.
School of Nursing, Yangzhou University, Yangzhou, Jiangsu Province, China.
J Eval Clin Pract. 2025 Mar;31(2):e14133. doi: 10.1111/jep.14133. Epub 2024 Sep 5.
People diagnosed with Inflammatory bowel disease (IBD) often have severe dietary restrictions and avoidance due to the uncertainty of intestinal symptoms. Inadequate dietary intake may increase the risk of malnutrition and result in impaired food-related quality of life (FRQoL). Few studies investigated factors influencing FRQoL in patients with IBD. This study aimed to synthesize the existing evidence regarding FRQoL among patients with IBD, including the current situation, measurement instruments, and related influencing factors.
The comprehensive literature search was conducted in databases including PubMed, Embase, CINAHL, PsycInfo, Cochrane Library, as well as the most commonly used Chinese databases (CNKI, Wanfang and CBM). Studies published between January 2015 and December 2023 on FRQoL in patients with IBD were included. The Joanna Briggs Institute (JBI) critical appraisal checklist was utilized to evaluate the methodological quality of the selected studies.
Finally, only five studies met the inclusion criteria were reviewed, including three cross-sectional studies and two case-control studies. The Food-related quality of life-29 Scale (FR-QoL-29) with a total core of 145 was the most used instrument measuring FRQoL in patients with IBD. The mean scores of FRQoL ranged from 69.9 to 102.3 in adult patients with IBD and 94.3 in children. A diverse range of factors were associated with FRQoL, including socio-demographic, clinical, psychological, diet-related, and nutrient intake factors.
The main influencing factors of FRQoL among patients with IBD included disease activity status, severe symptoms, history of IBD surgery, negative emotion reaction, and restrictive eating behaviour. Clinicians should work in concert with dietitians, keeping an eye on the disease status, nutrition intake, and restrictive eating habits, assessing FRQoL and providing personalized dietary recommendation for the patients with IBD.
由于肠道症状的不确定性，被诊断为炎症性肠病（IBD）的患者通常有严格的饮食限制和禁忌。饮食摄入不足可能会增加营养不良的风险，并导致与食物相关的生活质量（FRQoL）受损。很少有研究调查影响IBD患者FRQoL的因素。本研究旨在综合关于IBD患者FRQoL的现有证据，包括现状、测量工具和相关影响因素。
在包括PubMed、Embase、CINAHL、PsycInfo、Cochrane图书馆以及最常用的中文数据库（CNKI、万方和CBM）在内的数据库中进行全面的文献检索。纳入2015年1月至2023年12月发表的关于IBD患者FRQoL的研究。采用乔安娜·布里格斯研究所（JBI）批判性评价清单来评估所选研究的方法学质量。
最后，仅对五项符合纳入标准的研究进行了综述，包括三项横断面研究和两项病例对照研究。总核心分为145分的食物相关生活质量-29量表（FR-QoL-29）是测量IBD患者FRQoL最常用的工具。IBD成年患者的FRQoL平均得分在69.9至102.3之间，儿童为94.3。多种因素与FRQoL相关，包括社会人口统计学、临床、心理、饮食相关和营养摄入因素。
IBD患者FRQoL的主要影响因素包括疾病活动状态、严重症状、IBD手术史、负面情绪反应和限制性饮食行为。临床医生应与营养师合作，关注疾病状态、营养摄入和限制性饮食习惯，评估FRQoL并为IBD患者提供个性化的饮食建议。
