IEEE Trans Image Process. 2024;33:4882-4895. doi: 10.1109/TIP.2024.3451934. Epub 2024 Sep 11.
Unsupervised domain adaptation medical image segmentation is aimed to segment unlabeled target domain images with labeled source domain images. However, different medical imaging modalities lead to large domain shift between their images, in which well-trained models from one imaging modality often fail to segment images from anothor imaging modality. In this paper, to mitigate domain shift between source domain and target domain, a style consistency unsupervised domain adaptation image segmentation method is proposed. First, a local phase-enhanced style fusion method is designed to mitigate domain shift and produce locally enhanced organs of interest. Second, a phase consistency discriminator is constructed to distinguish the phase consistency of domain-invariant features between source domain and target domain, so as to enhance the disentanglement of the domain-invariant and style encoders and removal of domain-specific features from the domain-invariant encoder. Third, a style consistency estimation method is proposed to obtain inconsistency maps from intermediate synthesized target domain images with different styles to measure the difficult regions, mitigate domain shift between synthesized target domain images and real target domain images, and improve the integrity of interested organs. Fourth, style consistency entropy is defined for target domain images to further improve the integrity of the interested organ by the concentration on the inconsistent regions. Comprehensive experiments have been performed with an in-house dataset and a publicly available dataset. The experimental results have demonstrated the superiority of our framework over state-of-the-art methods.
无监督域自适应医学图像分割旨在使用有标签的源域图像对未标记的目标域图像进行分割。然而,不同的医学成像模态导致它们的图像之间存在较大的域偏移,其中来自一种成像模态的训练良好的模型通常无法对来自另一种成像模态的图像进行分割。在本文中,为了减轻源域和目标域之间的域偏移,提出了一种样式一致性无监督域自适应图像分割方法。首先,设计了一种局部相位增强样式融合方法,以减轻域偏移并生成局部增强的感兴趣器官。其次,构建了一个相位一致性鉴别器,以区分源域和目标域之间域不变特征的相位一致性,从而增强域不变和样式编码器的解缠,并从域不变编码器中去除特定于域的特征。第三,提出了一种样式一致性估计方法,从具有不同样式的中间合成目标域图像中获得不一致性图,以测量困难区域,减轻合成目标域图像和真实目标域图像之间的域偏移,并提高感兴趣器官的完整性。第四,为目标域图像定义了样式一致性熵,通过集中在不一致区域来进一步提高感兴趣器官的完整性。使用内部数据集和公开数据集进行了全面的实验。实验结果表明,我们的框架优于最先进的方法。