Faculty of Pharmacy, Integral University, Lucknow, India.
Maharishi University of Information Technology, Lucknow, India.
Contemp Clin Trials. 2024 Nov;146:107684. doi: 10.1016/j.cct.2024.107684. Epub 2024 Sep 3.
Clinical drug trials are intricate, involving numerous stakeholders, substantial data, and stringent regulations. Traditional systems for recording, storing, and sharing trial data often face data integrity, transparency, security, and interoperability challenges. The utilization of blockchain technology has emerged as a transformative influence in various industries, and its potential within healthcare, particularly in clinical drug trials, is increasingly gaining recognition.
Blockchain technology presents a decentralized and immutable ledger system that holds promise in effectively addressing these challenges. As the healthcare industry continues its journey of digital transformation, the incorporation of blockchain technology for monitoring clinical drug trials represents a paradigm shift that can result in more reliable, efficient, and transparent trials.
This review explores the innovative application of blockchain technology in transforming the monitoring and management of clinical drug trials and provides a comprehensive overview of the possibilities, challenges, and future directions of blockchain-based monitoring in the context of clinical drug trials, contributing to the progress of both blockchain technology and healthcare research practices.
临床药物试验错综复杂，涉及众多利益相关者、大量数据和严格的法规。传统的试验数据记录、存储和共享系统常常面临数据完整性、透明度、安全性和互操作性方面的挑战。区块链技术在各个行业的应用已经产生了变革性的影响，其在医疗保健领域，特别是在临床药物试验中的应用潜力正日益受到关注。
区块链技术提供了一个去中心化且不可篡改的账本系统，有望有效地解决这些挑战。随着医疗保健行业数字化转型的持续推进，将区块链技术应用于临床药物试验监测代表了一种范式转变，可以实现更可靠、高效和透明的试验。
本综述探讨了区块链技术在改变临床药物试验监测和管理方面的创新应用，并全面概述了基于区块链的监测在临床药物试验背景下的可能性、挑战和未来方向，为区块链技术和医疗保健研究实践的发展做出了贡献。
