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CONUT 评分对老年慢性心力衰竭患者预后的影响。

Prognostic impact of CONUT score in older patients with chronic heart failure.

机构信息

Department of Clinical Nutrition, Huadong Hospital affiliated to Fudan University, Shanghai, China.

Division of Medicine, University College London, London, UK.

出版信息

BMC Geriatr. 2024 Sep 5;24(1):738. doi: 10.1186/s12877-024-05330-5.

Abstract

BACKGROUND

Malnutrition is common in older patients with chronic heart failure (HF) and often accompanies a deterioration of their condition. The Controlling Nutritional Status (CONUT) score is used as an objective indicator to evaluate nutritional status, but relevant research in this area is limited. This study aimed to report the prevalence, clinical correlates, and outcomes of malnutrition in elder patients hospitalized with chronic HF.

METHODS

A retrospective analysis was conducted on 165 eligible patients admitted to the Department of Cardiology at Huadong Hospital from January 2021 to December 2022. Patients were categorized based on their CONUT score into three groups: normal nutrition status, mild risk of malnutrition, and moderate to severe risk of malnutrition. The study examined the nutritional status of this population and its relationship with clinical outcomes.

RESULTS

Findings revealed that malnutrition affected 82% of the older patients, with 28% experiencing moderate to severe risk. Poor nutritional scores were significantly associated with prolonged hospital stay, increased in-hospital mortality and all-cause mortality during readmissions within one year (P < 0.05). The multivariable analysis indicated that moderate to severe malnutrition (CONUT score of 5-12) was significantly associated with a heightened risk of prolonged hospitalization (aOR: 9.17, 95%CI: 2.02-41.7).

CONCLUSIONS

Malnutrition, as determined by the CONUT score, is a common issue among HF patients. Utilizing the CONUT score upon admission can effectively predict the potential for prolonged hospital stays.

摘要

背景

营养不良在患有慢性心力衰竭(HF)的老年患者中很常见,并且常常伴随着病情的恶化。控制营养状况(CONUT)评分被用作评估营养状况的客观指标,但该领域的相关研究有限。本研究旨在报告慢性 HF 住院老年患者营养不良的患病率、临床相关性和结局。

方法

对 2021 年 1 月至 2022 年 12 月在华东医院心内科住院的 165 名符合条件的患者进行回顾性分析。根据 CONUT 评分将患者分为三组:营养状况正常、轻度营养不良风险和中重度营养不良风险。研究检查了该人群的营养状况及其与临床结局的关系。

结果

研究结果显示,营养不良影响了 82%的老年患者,其中 28%的患者存在中重度营养不良风险。营养评分较差与住院时间延长、住院期间死亡率增加以及一年内再次入院的全因死亡率增加显著相关(P<0.05)。多变量分析表明,中重度营养不良(CONUT 评分 5-12)与住院时间延长的风险显著增加相关(aOR:9.17,95%CI:2.02-41.7)。

结论

CONUT 评分确定的营养不良是 HF 患者的常见问题。入院时使用 CONUT 评分可以有效预测住院时间延长的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2845/11378522/d94c094f9451/12877_2024_5330_Fig1_HTML.jpg

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