Jewell L D, Fields A L, Murray C J, Thomson A B
Am J Gastroenterol. 1985 Jun;80(6):421-4.
We report the case of a 59-year-old man who was treated with intraarterial chemotherapy for metastatic colonic adenocarcinoma. After the second course he developed persistent symptoms of nausea, vomiting, and pain. Endoscopic examination demonstrated severe erosive gastritis and duodenitis, and histological examination of the antral tissue showed severe atypia and histological appearances suggestive of in situ carcinoma. A 2-month course of sucralfate and cimetidine was used and successfully produced symptomatic relief as well as complete normalization of the dysplastic changes.
我们报告了一例59岁男性患者，其因转移性结肠腺癌接受动脉内化疗。在第二个疗程后，他出现了持续的恶心、呕吐和疼痛症状。内镜检查显示严重的糜烂性胃炎和十二指肠炎，胃窦组织的组织学检查显示严重异型性和提示原位癌的组织学表现。使用了为期2个月的硫糖铝和西咪替丁疗程，成功缓解了症状，并使发育异常改变完全恢复正常。
