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[1例结肠腺癌伴肝转移经动脉灌注化疗后的长期生存病例]

[A long survival case of carcinoma of the colon with hepatic metastasis following intra-arterial infusion chemotherapy].

作者信息

Itoh J, Masuda T, Narisawa T, Koyama K

出版信息

Gan To Kagaku Ryoho. 1985 Aug;12(8):1681-5.

PMID:3927849
Abstract

A 61-year-old man with double colon cancers and a solitary hepatic metastasis underwent right hemicolectomy and catheterization of the proper hepatic artery in April 1979. Intraarterial infusion chemotherapy of 5-FU, to a total of 8,000 mg, and Mitomycin C, to a total of 40 mg, was performed for thirty-two days. During chemotherapy, calcification appeared and occupied the metastatic lesion. The patient is presently in good health and has been disease-free for five years and nine months. In this case, it was supposed that obstruction of the peripheral tumor vessels was the most important causative factor of tumor calcification. This case was clinically valuable because tumor calcification proved to be a marker of tendency toward cure and complete cure of cancer.

摘要

一名61岁男性患有双结肠癌并伴有孤立性肝转移,于1979年4月接受了右半结肠切除术及肝固有动脉插管术。进行了为期32天的动脉内灌注化疗,5-氟尿嘧啶总量达8000毫克,丝裂霉素C总量达40毫克。化疗期间,出现钙化并占据了转移灶。该患者目前身体健康,已无病生存五年零九个月。在本病例中,推测肿瘤外周血管阻塞是肿瘤钙化的最重要致病因素。该病例具有临床价值,因为肿瘤钙化被证明是癌症治愈倾向和完全治愈的一个标志。

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