Department of Internal Medicine - Nephrology, University of Michigan, Ann Arbor, Michigan, USA.
Department of Surgery, University of Florida, Jacksonville, Florida, USA.
Clin Transplant. 2024 Sep;38(9):e15452. doi: 10.1111/ctr.15452.
Deceased donor organs for transplantation are costly. Expenses include donor assessment, pre-operative care of acceptable donors, surgical organ recovery, preservation and transport, and other costs. US Organ Procurement Organizations (OPOs) serve defined geographic areas in which each OPO has exclusive organ recovery responsibilities including detailed reporting of costs. We sought to determine the costs of procuring deceased donor livers by examining reported organ acquisition costs from OPO cost reports. Using 6 years of US OPO cost report data for each OPO (2013-2018), we determined the average cost of recovering a viable (i.e., transplanted) liver for each of the 51 independent US OPOs. We examined predictors of these costs including the number of livers procured, the percent of nonviable livers, direct procurement costs, coordinator salaries, professional education, and local cost of living. A cost curve estimated the relationship between the cost of livers and the number of locally procured livers. The average cost of procured livers by individual OPO-year varied widely from $11 393 to $65 556 (average $31 659) over the six study years. An increase in the overall number of procured livers was associated with lower direct costs, administrative, and procurement overhead costs, but this association differed for imported livers. Cost per local liver decreased linearly for each additional liver, while importing more livers was only cost saving until 200 livers, with imported livers costing more ($39K vs. $31.7K). The largest predictor of variation in cost was the aggregate of direct costs (e.g., hospital costs) to recover the organ (57%). Cost increases were 2.5% per year (+$766/year). This information may be valuable in determining how OPOs might improve service to transplant centers and the patients they serve.
用于移植的已故供体器官费用昂贵。这些费用包括供体评估、可接受供体的术前护理、手术器官回收、保存和运输,以及其他费用。美国器官获取组织(OPO)服务于特定的地理区域,每个 OPO 都有独家的器官回收责任,包括详细报告成本。我们试图通过检查 OPO 成本报告中报告的器官获取成本来确定获取已故供体肝脏的成本。使用每个 OPO 的 6 年美国 OPO 成本报告数据(2013-2018 年),我们确定了 51 个独立的美国 OPO 中每个 OPO 回收一个可行(即移植)肝脏的平均成本。我们研究了这些成本的预测因素,包括获取的肝脏数量、不可用肝脏的百分比、直接采购成本、协调员工资、专业教育和当地生活成本。成本曲线估计了肝脏成本与当地采购肝脏数量之间的关系。单个 OPO 年的采购肝脏的平均成本在六年的研究期间差异很大,从 11393 美元到 65556 美元不等(平均为 31659 美元)。整体采购肝脏数量的增加与直接成本、行政和采购间接成本的降低有关,但对于进口肝脏来说,这种关联不同。每增加一个本地肝脏,成本就会线性下降,而进口更多肝脏只有在 200 个肝脏之前才具有成本效益,进口肝脏的成本更高(39K 美元与 31.7K 美元)。成本变化的最大预测因素是回收器官的直接成本总和(例如,医院成本)(57%)。成本每年增加 2.5%(每年增加 766 美元)。这些信息对于确定 OPO 如何改善对移植中心及其服务患者的服务可能很有价值。