Amatto Alycia, Smith Ashley, Pan Bo, Al Hamarneh Yazid, Burnham Taylor, Burnham Robert
Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Vivo Cura Health, Calgary, Alberta, Canada.
Interv Pain Med. 2022 Jul 8;1(3):100116. doi: 10.1016/j.inpm.2022.100116. eCollection 2022 Sep.
The Pain Disability Quality-Of-Life Questionnaire-Spine (PDQQ-S) is a validated six question patient reported outcome measure designed for usage in minimally invasive spine intervention. The purpose of this study was to determine the Minimal Clinically Important Difference (MCID) for the PDQQ-S.
Retrospective single arm cohort study involving 411 patients who had undergone lumbar facet and/or sacroiliac joint RFN and had completed pre-and 3-month post RFN PDQQ-S.
The MCID using both distribution and anchor-based ("Rebook RFN"; "Analgesic Requirements") methods were calculated.
The distribution-based approach (using standard error of measurement) estimated the MCID to be -17.3 [PDQQ-S baseline mean (SD): 46.9 (7.9)]. This is supported by the anchor based approach, which calculated the MCID to be: -21.5 for rebook RFN; -11.3, -17.2 and -30.5 for mildly, moderately and dramatically decreased NSAID use respectively; and -11.7, -16.9 and -31.7 for mildly, moderately and dramatically decreased opioid use respectively. A moderate reduction in medication use was deemed to be clinically relevant.
The MCID value for the PDQQ-S is a score reduction of 17.
疼痛残疾生活质量问卷-脊柱版（PDQQ-S）是一项经过验证的包含六个问题的患者报告结局指标，专为微创脊柱干预设计。本研究的目的是确定PDQQ-S的最小临床重要差异（MCID）。
回顾性单臂队列研究，纳入411例接受腰椎小关节和/或骶髂关节射频神经毁损术（RFN）并在RFN术前和术后3个月完成PDQQ-S问卷的患者。
采用分布法和基于锚定法（“重新预约RFN”；“镇痛需求”）计算MCID。
基于分布的方法（使用测量标准误差）估计MCID为-17.3[PDQQ-S基线均值（标准差）：46.9（7.9）]。基于锚定的方法也支持这一结果，该方法计算出的MCID为：重新预约RFN时为-21.5；非甾体抗炎药（NSAID）使用轻度、中度和显著减少时分别为-11.3、-17.2和-30.5；阿片类药物使用轻度、中度和显著减少时分别为-11.7、-16.9和-31.7。药物使用的适度减少被认为具有临床相关性。
PDQQ-S的MCID值为分数降低17分。
