Civitarese David, Stephens Andrew, Curtis Timothy M, Young Chase, Ries Alexa G, Cooper Amanda N, Martin Brook, Amatto Alycia, Burnham Robert S, Conger Aaron M, McCormick Zachary L, Burnham Taylor R
Shirley Ryan AbilityLab, Chicago, IL, USA.
Department of Physical Medicine and Rehabilitation, University of Rochester, Rochester, NY, USA.
Interv Pain Med. 2025 Mar 19;4(1):100572. doi: 10.1016/j.inpm.2025.100572. eCollection 2025 Mar.
Cervical medial branch radiofrequency neurotomy (CMBRFN) with a parallel approach has been proven to be an effective treatment for zygapophyseal joint-mediated cervical pain. Technological advancements in radiofrequency probe design have allowed for a perpendicular approach to electrode placement. However, the effectiveness of the perpendicular approach remains to be fully understood.
Evaluate the effectiveness of CMBRFN with a perpendicular approach (pCMBRFN) in patients with confirmed zygapophyseal joint-mediated cervical pain.
This single-arm, retrospective cohort study included patients identified between 2016 and 2022 who underwent pCMBRFN after demonstrating ≥80 % pain relief with two consecutive diagnostic medial branch blocks (MBB). Primary outcomes were ≥50 % patient-reported numeric rating scale (NRS) pain relief and minimal clinically important difference (MCID) on the Pain Disability Quality-Of-Life Questionnaire-Spine (PDQQ-S) at 3 months post-procedure. Secondary outcomes were mean patient-reported retrospective percentage pain relief and duration of relief after a successful pCMBRFN in individuals who presented for repeat pCMBRFN upon return of their symptoms.
A total of 52 participants (63.5 % female; mean age 55.9 ± 10.9 years; mean BMI 26.8 ± 5.2 kg/m) were analyzed. At 3 months post-procedure, ≥50 % NRS pain reduction and MCID on PDQQ-S were both reported by 34 patients (65.4 % [95%CI 51.8-76.9]). Of the 34 patients with successful treatment response, 15 had return of symptoms after an average of 8.8 ± 2.5 months with a reported mean percentage pain relief of 86.0 ± 14.9 %.
Within this cohort, pCMBRFN demonstrated effectiveness by reducing pain and disability in over 65 % of patients with confirmed cervical zygapophyseal joint-mediated pain at 3 months. Patients with successful treatment outcomes whose index symptoms eventually returned reported an average pain reduction of 86 % lasting approximately 9 months. Larger prospective studies with long-term follow-up are needed to confirm these results.
经证实,采用平行入路的颈椎内侧支射频神经切断术(CMBRFN)是治疗关节突关节介导的颈部疼痛的有效方法。射频探头设计的技术进步使得电极放置可以采用垂直入路。然而,垂直入路的有效性仍有待充分了解。
评估采用垂直入路的CMBRFN(pCMBRFN)对确诊为关节突关节介导的颈部疼痛患者的有效性。
这项单臂回顾性队列研究纳入了2016年至2022年间确诊的患者,这些患者在连续两次诊断性内侧支阻滞(MBB)后疼痛缓解≥80%,随后接受了pCMBRFN。主要结局指标为术后3个月时患者报告的数字评定量表(NRS)疼痛缓解≥50%,以及在疼痛残疾生活质量问卷-脊柱版(PDQQ-S)上达到最小临床重要差异(MCID)。次要结局指标为患者报告的回顾性平均疼痛缓解百分比,以及症状复发后再次接受pCMBRFN的患者成功接受pCMBRFN后的缓解持续时间。
共分析了52名参与者(63.5%为女性;平均年龄55.9±10.9岁;平均BMI 26.8±5.2kg/m)。术后3个月时,34名患者(65.4%[95%CI 51.8-76.9])报告NRS疼痛减轻≥50%且在PDQQ-S上达到MCID。在34例治疗反应成功的患者中,15例在平均8.8±2.5个月后症状复发,报告的平均疼痛缓解百分比为86.0±14.9%。
在该队列中,pCMBRFN在术后3个月时对超过65%确诊为颈椎关节突关节介导疼痛的患者显示出减轻疼痛和残疾的有效性。治疗结果成功但初始症状最终复发的患者报告平均疼痛减轻86%,持续约9个月。需要进行更大规模的长期随访前瞻性研究来证实这些结果。