• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Pain-induced autonomic dysreflexia secondary to spinal cord injury with significant improvement after spinal cord stimulator implantation.脊髓损伤继发疼痛性自主神经反射异常,脊髓刺激器植入后有显著改善。
Interv Pain Med. 2023 May 26;2(2):100254. doi: 10.1016/j.inpm.2023.100254. eCollection 2023 Jun.
2
Autonomic dysreflexia during urodynamics in children and adolescents with spinal cord injury or severe neurologic disease.脊髓损伤或严重神经疾病的儿童及青少年在尿动力学检查期间的自主神经反射异常
J Pediatr Urol. 2015 Feb;11(1):32.e1-4. doi: 10.1016/j.jpurol.2014.08.011. Epub 2014 Oct 8.
3
Spinal Cord Injury and Autonomic Dysreflexia: A Case Report on an Overlooked Complication of Spinal Cord Injury.脊髓损伤与自主神经反射异常:一例关于脊髓损伤被忽视并发症的病例报告
Cureus. 2022 Oct 13;14(10):e30259. doi: 10.7759/cureus.30259. eCollection 2022 Oct.
4
Differential target multiplexed spinal cord stimulation using a paddle-type lead placed at the appropriate site for neuropathic pain after spinal cord injury in patients with past spinal surgical histories: study protocol for an exploratory clinical trial.利用过去有过脊柱手术史的脊髓损伤后神经性疼痛患者合适部位放置的板状电极进行差异靶向脊髓刺激:一项探索性临床试验的研究方案。
Trials. 2023 Jun 13;24(1):395. doi: 10.1186/s13063-023-07433-7.
5
Spinal Cord Stimulation Prevents Autonomic Dysreflexia in Individuals with Spinal Cord Injury: A Case Series.脊髓刺激预防脊髓损伤患者的自主神经反射异常:病例系列
J Clin Med. 2023 Apr 16;12(8):2897. doi: 10.3390/jcm12082897.
6
Spinal cord stimulation for neuropathic pain: an evidence-based analysis.脊髓刺激治疗神经性疼痛:一项基于证据的分析。
Ont Health Technol Assess Ser. 2005;5(4):1-78. Epub 2005 Mar 1.
7
Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury.脊髓内可溶性 TNFα 信号转导参与脊髓损伤后自主反射障碍的发生发展以及随后的血管和免疫功能障碍。
J Neurosci. 2018 Apr 25;38(17):4146-4162. doi: 10.1523/JNEUROSCI.2376-17.2018. Epub 2018 Apr 2.
8
Takotsubo cardiomyopathy in a chronic spinal cord injury patient with autonomic dysreflexia: A case report.慢性脊髓损伤伴自主神经反射不良患者的 Takotsubo 心肌病:病例报告。
J Spinal Cord Med. 2021 Nov;44(6):1026-1029. doi: 10.1080/10790268.2020.1724355. Epub 2020 Feb 11.
9
1-kHz high-frequency spinal cord stimulation alleviates chronic refractory pain after spinal cord injury: a case report.1千赫兹高频脊髓刺激缓解脊髓损伤后的慢性难治性疼痛:一例报告
JA Clin Rep. 2021 Jun 8;7(1):46. doi: 10.1186/s40981-021-00451-x.
10
Spinal cord stimulation in patients suffering from chronic pain after surgery for spinal intradural tumors: A case report and literature summary.脊髓刺激治疗脊髓髓内肿瘤术后慢性疼痛患者:病例报告及文献综述。
Pain Pract. 2022 Nov;22(8):746-752. doi: 10.1111/papr.13156. Epub 2022 Aug 30.

引用本文的文献

1
Preemptive Propofol Administration in Spinal Cord Injury: Effects on Pain-Induced Hypertension, Neuroinflammation, and Functional Recovery in Rats.脊髓损伤中丙泊酚的预防性给药:对大鼠疼痛诱导的高血压、神经炎症和功能恢复的影响
Kaohsiung J Med Sci. 2025 Jun;41(6):e70011. doi: 10.1002/kjm2.70011. Epub 2025 Apr 1.

本文引用的文献

1
Autonomic Dysreflexia following Spinal Cord Injury.脊髓损伤后的自主神经反射异常
Asian J Neurosurg. 2022 Aug 25;17(2):165-172. doi: 10.1055/s-0042-1751080. eCollection 2022 Jun.
2
Spinal Cord Stimulation Research in the Restoration of Motor, Sensory, and Autonomic Function for Individuals Living With Spinal Cord Injuries: A Scoping Review.脊髓损伤患者运动、感觉和自主功能恢复的脊髓刺激研究:范围综述。
Arch Phys Med Rehabil. 2022 Jul;103(7):1387-1397. doi: 10.1016/j.apmr.2022.01.161. Epub 2022 Feb 23.
3
Toward rebalancing blood pressure instability after spinal cord injury with spinal cord electrical stimulation: A mini review and critique of the evolving literature.针对脊髓损伤后血压不稳定的脊髓电刺激再平衡:对不断发展的文献的小型综述和批评。
Auton Neurosci. 2022 Jan;237:102905. doi: 10.1016/j.autneu.2021.102905. Epub 2021 Nov 11.
4
Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.高频(10kHz)脊髓刺激治疗糖尿病性神经痛的疗效:一项随机临床试验。
JAMA Neurol. 2021 Jun 1;78(6):687-698. doi: 10.1001/jamaneurol.2021.0538.
5
Spinal Cord Stimulation.脊髓刺激
Neurosurg Clin N Am. 2019 Apr;30(2):169-194. doi: 10.1016/j.nec.2018.12.003. Epub 2019 Feb 18.
6
Epidural Spinal Cord Stimulation Facilitates Immediate Restoration of Dormant Motor and Autonomic Supraspinal Pathways after Chronic Neurologically Complete Spinal Cord Injury.硬膜外脊髓电刺激促进慢性完全性脊髓损伤后休眠的运动和自主神经上位通路的即刻恢复。
J Neurotrauma. 2019 Aug 1;36(15):2325-2336. doi: 10.1089/neu.2018.6006. Epub 2019 Mar 6.
7
Spinal Cord Stimulation: Clinical Efficacy and Potential Mechanisms.脊髓刺激:临床疗效与潜在机制
Pain Pract. 2018 Nov;18(8):1048-1067. doi: 10.1111/papr.12692. Epub 2018 Apr 23.
8
Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management.脊髓损伤后的自主神经反射异常:全身病理生理学及管理方法
Auton Neurosci. 2018 Jan;209:59-70. doi: 10.1016/j.autneu.2017.05.002. Epub 2017 May 8.
9
How is chronic pain related to sympathetic dysfunction and autonomic dysreflexia following spinal cord injury?脊髓损伤后,慢性疼痛与交感神经功能障碍及自主神经反射异常有何关联?
Auton Neurosci. 2018 Jan;209:79-89. doi: 10.1016/j.autneu.2017.01.006. Epub 2017 Jan 27.
10
Neuropathic pain following traumatic spinal cord injury: Models, measurement, and mechanisms.创伤性脊髓损伤后的神经性疼痛:模型、测量与机制
J Neurosci Res. 2017 Jun;95(6):1295-1306. doi: 10.1002/jnr.23881. Epub 2016 Sep 12.

脊髓损伤继发疼痛性自主神经反射异常,脊髓刺激器植入后有显著改善。

Pain-induced autonomic dysreflexia secondary to spinal cord injury with significant improvement after spinal cord stimulator implantation.

作者信息

Dzierzak Ellen, Mamun Noushad, Cohen Jackson, Delgado-Lebron Joanne

机构信息

Department of Physical Medicine and Rehabilitation at Memorial Healthcare System, 3702 Washington Street, Suite 303, Hollywood, FL, 33021, USA.

出版信息

Interv Pain Med. 2023 May 26;2(2):100254. doi: 10.1016/j.inpm.2023.100254. eCollection 2023 Jun.

DOI:10.1016/j.inpm.2023.100254
PMID:39238671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11373029/
Abstract

INTRODUCTION

Spinal cord stimulation (SCS) has been established as a safe and effective alternative treatment for many conditions. This is a unique case involving SCS in spinal cord injury (SCI) patients with recurrent episodes of autonomic dysreflexia (AD). AD is a sympathetically driven reflexive hypertension in response to a noxious stimuli below the neurological level of spinal cord injury. There is currently limited research and literature regarding SCS application for AD. We present a unique case where pain-induced AD was successfully treated with implantation of SCS, in order to avoid long term opioid use and improve quality of life.

CASE PRESENTATION

We present a 46-year-old female, with history of chronic incomplete traumatic quadriplegia, with increased frequency of symptomatic AD. After an extensive work-up, it was determined that the likely trigger for the AD episodes was neuropathic and nociceptive pain below the level of the spinal cord injury. Due to the frequency of AD episodes, uncontrolled pain, and concerns of long term opioid usage, she was referred for an evaluation for possible SCS placement. The patient ultimately underwent SCS implantation and battery revision. She had significant improvement of AD episodes after SCS implantation.

CONCLUSION

This case identifies a unique approach to preventing AD episodes by addressing intractable neuropathic pain with SCS.

摘要

引言

脊髓刺激(SCS)已被确立为许多病症的一种安全有效的替代治疗方法。这是一个独特的病例,涉及脊髓损伤(SCI)患者反复出现自主神经反射异常(AD)发作时的SCS治疗。AD是一种由交感神经驱动的反射性高血压,由脊髓损伤神经平面以下的有害刺激引发。目前关于SCS用于AD治疗的研究和文献有限。我们呈现一个独特病例,其中疼痛诱发的AD通过植入SCS成功得到治疗,以避免长期使用阿片类药物并提高生活质量。

病例介绍

我们介绍一名46岁女性,有慢性不完全创伤性四肢瘫病史,症状性AD发作频率增加。经过全面检查,确定AD发作的可能触发因素是脊髓损伤平面以下的神经性和伤害性疼痛。由于AD发作频率、疼痛控制不佳以及对长期使用阿片类药物的担忧,她被转介进行可能的SCS植入评估。患者最终接受了SCS植入和电池更换。植入SCS后,她的AD发作有显著改善。

结论

本病例确定了一种通过使用SCS解决顽固性神经性疼痛来预防AD发作的独特方法。