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当预期变为意外:甲状腺功能减退症的急性表现

When the Expected Becomes Unexpected: An Acute Presentation of Hypothyroidism.

作者信息

Martinez Sanchez Andrea, Vega Castellvi Claudia, Tarkoff Joshua, De La Vega Christie

机构信息

Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL 33155, USA.

出版信息

JCEM Case Rep. 2024 Sep 5;2(9):luae154. doi: 10.1210/jcemcr/luae154. eCollection 2024 Sep.

Abstract

Myxedema coma is an uncommon and life-threatening manifestation of severe hypothyroidism. Its occurrence in the pediatric population is exceptionally rare and can result from long-standing untreated hypothyroidism or nonadherence to treatment. Identifying this condition can be challenging because it requires a high level of clinical suspicion along with thyroid function testing. We present a 17-year-old female with a history of anxiety who had widespread nonspecific symptoms, including persistent bradycardia, which were found to be caused by hypothyroidism. Our goal is to raise awareness of the varied clinical manifestations of pediatric myxedema to promote early recognition and prompt medical interventions that can lead to better outcomes.

摘要

黏液性水肿昏迷是严重甲状腺功能减退症的一种罕见且危及生命的表现。它在儿科人群中极为罕见,可能由长期未治疗的甲状腺功能减退症或不坚持治疗引起。识别这种情况具有挑战性,因为它需要高度的临床怀疑以及甲状腺功能测试。我们报告了一名17岁有焦虑病史的女性,她有广泛的非特异性症状,包括持续性心动过缓,后来发现是由甲状腺功能减退症引起的。我们的目标是提高对儿科黏液性水肿各种临床表现的认识,以促进早期识别和及时的医疗干预,从而带来更好的结果。

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