Ma Ran, Wang Yan-Mei, Guan Hua, Zhang Li, Zhang Wei, Chen Ling-Cai
Department of Pediatrics, Shihezi University, Shihezi 832000, Xinjiang Uygur Autonomous Region, China.
Department of Pediatrics, The First Affiliated Hospital of Shihezi University, Shihezi 832000, Xinjiang Uygur Autonomous Region, China.
World J Radiol. 2024 Aug 28;16(8):362-370. doi: 10.4329/wjr.v16.i8.362.
Lung abscess found on chest X-ray and computed tomography examinations is rare in infants and young children. Several pathogens can cause lung abscesses, with the most common pathogens being anaerobes, and () is a member of the family, and is mainly isolated from respiratory tract specimens. There are currently no cases of lung abscess caused by in the literature.
A 2-year-old boy was admitted to hospital due to persistent cough and fever. Lung computed tomography examination suggested the formation of a lung abscess. His diagnosis was not confirmed by testing for serum respiratory pathogens (6 items), respiratory pathogen nucleic acid (27 items), and laboratory culture. Finally, metagenomic next-generation sequencing of bronchoalveolar lavage fluid revealed the presence of , confirming its role in causing the lung abscess. After receiving antibiotic treatment, reexamination with lung computed tomography showed that the abscess was resorbed and the patient's outcome was good.
This is the first report of a lung abscess in a child caused by infection. Metagenomic next-generation sequencing of bronchoalveolar lavage fluid is helpful in achieving rapid and accurate pathogen identification.
胸部X线和计算机断层扫描检查发现的肺脓肿在婴幼儿中很少见。几种病原体可导致肺脓肿，最常见的病原体是厌氧菌，（）是该菌属的成员，主要从呼吸道标本中分离出来。目前文献中尚无由（）引起肺脓肿的病例。
一名2岁男孩因持续咳嗽和发热入院。肺部计算机断层扫描检查提示肺脓肿形成。血清呼吸道病原体检测（6项）、呼吸道病原体核酸检测（27项）及实验室培养均未确诊。最后，支气管肺泡灌洗液体宏基因组下一代测序显示存在（），证实其在导致肺脓肿中的作用。接受抗生素治疗后，肺部计算机断层扫描复查显示脓肿吸收，患者预后良好。
这是首例关于儿童感染（）导致肺脓肿的报告。支气管肺泡灌洗液体宏基因组下一代测序有助于快速准确地鉴定病原体。
