Wentz Kyle, Chung Yu-Chen, Patel Ankit
UT Southwestern Medical Center, United States.
Interv Pain Med. 2022 May 26;1(2):100104. doi: 10.1016/j.inpm.2022.100104. eCollection 2022 Jun.
Lumbar spinal stenosis is a common finding in the adult population. Lumbar Epidural Steroid Injections (ESIs) are often used in management of this condition, with conflicting evidence regarding their efficacy. Previous research has suggested a negative impact of ESIs on the postoperative outcomes when ESIs are administered preoperatively prior to spine surgery in this population. Our retrospective study was performed to gain greater insight into the impact of preoperative ESIs on postoperative outcomes following spine surgery in management of lumbar stenosis.
Our objective is to determine how preoperative ESIs impact postoperative outcomes following spine surgery in management of lumbar stenosis.
Retrospective cohort involving 95 patients (39 patients who received ESI in the preoperative timeframe and 56 patients who did not) who underwent surgical management of lumbar stenosis. Data for patients with preoperative ESI was compared to those without preoperative ESI administration.
Institutional.
Not Applicable.
PROMIS (Patient-Reported Outcomes Measurement Information System) scores, VAS (Visual Analog Scale) pain scores, ODI (Oswestry Disability Index), NDI (Neck Disability Index).
At baseline (time of surgery), the ESI group had significantly higher ODI, PROMIS pain, PROMIS pain interference, VAS leg and lower PROMIS physical function, but no significant difference in PROMIS satisfaction, VAS back and NDI, compared to the Non-ESI group. At 3 months after surgery, both the ESI and Non-ESI groups demonstrated a significant decrease in VAS back, VAS leg, PROMIS pain and ODI from baseline scores. The improvement in PROMIS pain at 3 months after surgery was larger in the ESI group than the Non-ESI group.
Preoperative ESI administration did not lead to worsening of disability, function, or pain symptoms in the short-term postoperative period following surgical management of lumbar stenosis. Patients had short term improvements in radicular pain following surgical management of lumbar stenosis, regardless of preoperative ESI administration.
腰椎管狭窄症在成年人群中很常见。腰椎硬膜外类固醇注射(ESI)常用于这种疾病的治疗,但其疗效证据相互矛盾。先前的研究表明,在该人群中,脊柱手术前进行ESI会对术后结果产生负面影响。我们进行了一项回顾性研究,以更深入地了解术前ESI对腰椎管狭窄症手术治疗后术后结果的影响。
我们的目的是确定术前ESI如何影响腰椎管狭窄症手术治疗后的术后结果。
回顾性队列研究,涉及95例接受腰椎管狭窄症手术治疗的患者(39例在术前接受ESI,56例未接受)。将术前接受ESI的患者数据与未接受术前ESI的患者数据进行比较。
机构。
不适用。
患者报告结果测量信息系统(PROMIS)评分、视觉模拟量表(VAS)疼痛评分、Oswestry功能障碍指数(ODI)、颈部功能障碍指数(NDI)。
在基线(手术时),与非ESI组相比,ESI组的ODI、PROMIS疼痛、PROMIS疼痛干扰、VAS腿部疼痛和较低的PROMIS身体功能显著更高,但在PROMIS满意度、VAS背部疼痛和NDI方面无显著差异。术后3个月,ESI组和非ESI组的VAS背部疼痛、VAS腿部疼痛、PROMIS疼痛和ODI均较基线评分显著降低。术后3个月,ESI组的PROMIS疼痛改善程度大于非ESI组。
术前ESI给药在腰椎管狭窄症手术治疗后的短期术后期间不会导致残疾、功能或疼痛症状恶化。无论术前是否进行ESI给药,患者在腰椎管狭窄症手术治疗后神经根性疼痛均有短期改善。