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术前硬膜外类固醇注射与腰椎手术感染率和硬膜撕裂率增加无关。

Preoperative epidural steroid injections are not associated with increased rates of infection and dural tear in lumbar spine surgery.

作者信息

Koltsov Jayme C B, Smuck Matthew W, Alamin Todd F, Wood Kirkham B, Cheng Ivan, Hu Serena S

机构信息

Stanford University School of Medicine, 450 Broadway Street, Pavilion C, 4th Floor, Mail Code 6342, Redwood City, CA, 94063, USA.

出版信息

Eur Spine J. 2021 Apr;30(4):870-877. doi: 10.1007/s00586-020-06566-6. Epub 2020 Aug 13.

Abstract

PURPOSE

The study objectives were to use a large national claims data resource to examine rates of preoperative epidural steroid injections (ESI) in lumbar spine surgery and determine whether preoperative ESI or the timing of preoperative ESI is associated with rates of postoperative complications and reoperations.

METHODS

A retrospective longitudinal analysis of patients undergoing lumbar spine surgery for disc herniation and/or spinal stenosis was undertaken using the MarketScan® databases from 2007-2015. Propensity-score matched cohorts were constructed to compare rates of complications and reoperations in patients with and without preoperative ESI.

RESULTS

Within the year prior to surgery, 120,898 (46.4%) patients had a lumber ESI. The median time between ESI and surgery was 10 weeks. 23.1% of patients having preoperative ESI had more than one level injected, and 66.5% had more than one preoperative ESI treatment. Patients with chronic pain were considerably more likely to have an ESI prior to their surgery [OR 1.62 (1.54, 1.69), p < 0.001]. Patients having preoperative ESI within in close proximity to surgery did not have increased rates of infection, dural tear, neurological complications, or surgical complications; however, they did experience higher rates of reoperations and readmissions than those with no preoperative ESI (p < 0.001).

CONCLUSION

Half of patients undergoing lumbar spine surgery for stenosis and/or herniation had a preoperative ESI. These were not associated with an increased risk for postoperative complications, even when the ESI was given in close proximity to surgery. Patients with preoperative ESI were more likely to have readmissions and reoperations following surgery.

摘要

目的

本研究的目标是利用一个大型国家索赔数据资源,检查腰椎手术前硬膜外类固醇注射(ESI)的发生率,并确定术前ESI或术前ESI的时机是否与术后并发症和再次手术率相关。

方法

使用2007 - 2015年的MarketScan®数据库,对因椎间盘突出和/或椎管狭窄接受腰椎手术的患者进行回顾性纵向分析。构建倾向评分匹配队列,以比较有和没有术前ESI的患者的并发症和再次手术率。

结果

在手术前一年,120,898名(46.4%)患者接受了腰椎ESI。ESI与手术之间的中位时间为10周。接受术前ESI的患者中有23.1%注射了不止一个节段,66.5%接受了不止一次术前ESI治疗。慢性疼痛患者在手术前接受ESI的可能性显著更高[比值比1.62(1.54,1.69),p < 0.001]。在手术临近时接受术前ESI的患者,感染、硬脊膜撕裂、神经并发症或手术并发症的发生率并未增加;然而,与没有术前ESI的患者相比,他们的再次手术率和再入院率更高(p < 0.001)。

结论

因椎管狭窄和/或椎间盘突出接受腰椎手术的患者中有一半进行了术前ESI治疗。即使在手术临近时给予ESI,这些治疗也与术后并发症风险增加无关。术前接受ESI治疗的患者术后更有可能再次入院和接受再次手术。

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