Haydarpaşa Numune Education and Research Hospital, Sadik Eratik Eye Institute, Division of Glaucoma, University of Health Sciences, Istanbul, Turkey.
Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
Int Ophthalmol. 2024 Sep 6;44(1):373. doi: 10.1007/s10792-024-03287-3.
To evaluate radiographic lacrimal gland (LG) volume and dimensions in Ahmed glaucoma valve (AGV)- versus trabeculectomy-treated eyes and contralateral non-treated eyes.
In this retrospective cohort study, 1616 medical records acquired between 2010 and 2020 were examined. In AGV-treated (group 1) eyes, there were 19 patients with records sufficient for radiological LG evaluation, and in trabeculectomy-treated (group 2) eyes, there were 18. The hospital workstation software was used to assess high-resolution computed tomography (HRCT) scans conducted under standard protocol using a 128 SL Optima CT 660 scanner. The software (Vitrea™) was used to perform semi-quantitative volumetric measurements. LG dimensions were obtained in the axial and reformatted coronal planes on each side, and four measures were generated using the widest LG tip-to-tip diameters in two planes: coronal length, coronal width (CW), axial length (AL), and axial width.
The time interval between surgery and HRCT imaging was 50.97 ± 26.25 months. Group 1 had significantly lower LG volume than group 2 (594.11 ± 259.45 vs. 933.67 ± 294.09 mm, P = 0.001). When compared to non-treated eyes, AGV-treated eyes had lower LG volume (P = 0.065) while trabeculectomy-treated eyes had higher LG volume (P = 0.031). Further, group 1 had decreased length and width in both the axial and coronal planes as compared to group 2, with AL and CW being significantly different (P < 0.05).
AGV and trabeculectomy had varied impacts on LG volume and dimensions despite being conducted in the same quadrant. HRCT appears to be effective in analysing AGV position, which may be related to LG volumetric and dimensional issues.
评估 Ahmed 青光眼引流阀（AGV）-与小梁切除术治疗眼和对侧未治疗眼的泪腺（LG）的放射影像学体积和尺寸。
在这项回顾性队列研究中，检查了 2010 年至 2020 年间获得的 1616 份病历。在接受 AGV 治疗的（第 1 组）眼中，有 19 名患者的记录足以进行放射影像学 LG 评估，而在接受小梁切除术治疗的（第 2 组）眼中，有 18 名患者的记录足以进行放射影像学 LG 评估。使用医院工作站软件评估在标准协议下使用 128 层 Optima CT 660 扫描仪进行的高分辨率计算机断层扫描（HRCT）扫描。使用软件（Vitrea™）进行半定量容积测量。在每侧的轴位和重建成冠状位平面上获得 LG 尺寸，并在两个平面上使用最宽的 LG 尖端到尖端直径生成四个测量值：冠状长度、冠状宽度（CW）、轴向长度（AL）和轴向宽度。
手术与 HRCT 成像之间的时间间隔为 50.97±26.25 个月。第 1 组的 LG 体积明显低于第 2 组（594.11±259.45 与 933.67±294.09mm，P=0.001）。与未治疗眼相比，AGV 治疗眼的 LG 体积较低（P=0.065），而小梁切除术治疗眼的 LG 体积较高（P=0.031）。此外，与第 2 组相比，第 1 组在轴位和冠状位的长度和宽度均减小，AL 和 CW 差异有统计学意义（P<0.05）。
尽管在同一象限进行，但 AGV 和小梁切除术对 LG 体积和尺寸的影响不同。HRCT 似乎可有效分析 AGV 位置，这可能与 LG 体积和尺寸问题有关。
