揭开运动的奥秘：2型糖尿病患者增强胰岛素敏感性和骨骼肌健康的途径。
Unlocking the secrets of exercise: A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes.
作者信息
Zierath Juleen R, Brady Aidan J, Macgregor Kirstin A, de Zevallos Joaquin Ortiz, Stocks Ben
机构信息
Section of Integrative Physiology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 171 65, Sweden; Section of Integrative Physiology, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm 171 65, Sweden; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen 2200, Denmark.
Section of Integrative Physiology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 171 65, Sweden.
出版信息
J Sport Health Sci. 2024 Sep 4;14:100980. doi: 10.1016/j.jshs.2024.100980.
• Exercise impacts skeletal muscle and systemic metabolism, yet understanding the complex molecular mechanisms behind these effects remains a key research challenge. • Mapping the molecular effects of exercise with advanced “omics” can advance our understanding of muscle function and metabolism. • Exercise holds promise for managing and preventing type 2 diabetes, emphasizing the need for more research on individualized training and its molecular effects.
• 运动影响骨骼肌和全身代谢，但了解这些影响背后的复杂分子机制仍是一项关键的研究挑战。
• 用先进的“组学”技术描绘运动的分子效应，可增进我们对肌肉功能和代谢的理解。
• 运动有望用于管理和预防2型糖尿病，这凸显了对个性化训练及其分子效应开展更多研究的必要性。
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