Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Pelvic Cancer, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Hematol Oncol Clin North Am. 2024 Dec;38(6):1173-1190. doi: 10.1016/j.hoc.2024.07.003. Epub 2024 Sep 5.
Worldwide incidence rates of gestational trophoblastic disease (GTD) are difficult to estimate and compare due to large methodological differences within and between countries. Asia has generally reported higher incidence rates than Europe and North America, but modern reports have demonstrated a temporal decrease of GTD incidence rates in Asia and an increase in some European countries and North America. The main risk factors for hydatidiform mole are maternal age and previous molar events. Future studies on the epidemiology of GTD should include gestational trophoblastic neoplasia and international collaborative studies on this rare disease should be encouraged.
由于各国之间和各国内部方法学差异较大，难以估计和比较妊娠滋养细胞疾病（GTD）的全球发病率。亚洲的报告发病率一般高于欧洲和北美，但现代报告显示亚洲的 GTD 发病率呈下降趋势，而一些欧洲国家和北美的发病率则呈上升趋势。葡萄胎的主要危险因素是母亲年龄和既往葡萄胎事件。未来关于 GTD 流行病学的研究应包括妊娠滋养细胞肿瘤，应鼓励对这种罕见疾病开展国际合作研究。
